Form Equals Function: Influence of Coacervate Architecture on Drug Delivery Applications

C Lim, WC Blocher McTigue - ACS Biomaterials Science & …, 2024 - ACS Publications
Complex coacervates, formed through electrostatic interactions between oppositely charged
polymers, present a versatile platform for drug delivery, providing rapid assembly, selective …

Protease-Driven Phase Separation of Elastin-Like Polypeptides

BM Wirtz, AG Yun, C Wick, XJ Gao, DJ Mai - Biomacromolecules, 2024 - ACS Publications
Elastin-like polypeptides (ELPs) are a promising material platform for engineering stimuli-
responsive biomaterials, as ELPs undergo phase separation above a tunable transition …

β-Sheet Structure Formation within Binary Blends of Two Spider Silk Related Peptides

M Hofmaier, M Malanin, E Bittrich, S Lentz… - …, 2023 - ACS Publications
Intrinsically disordered proteins (IDPs) play an important role in molecular biology and
medicine because their induced folding can lead to so-called conformational diseases …

Thermal aggregation of immunoglobulin G depending on the charge state of protein–polyelectrolyte complexes

A Nomoto, K Shiraki - International Journal of Biological Macromolecules, 2025 - Elsevier
Protein–polyelectrolyte complexes (PPCs) exhibit opposite effects, both suppressing and
promoting protein aggregation, depending on the type of components. For the application of …

In Situ ATR-FTIR Studies on the β-Sheet Formation of Native and Regenerated Bombyx mori Silk Material in Solution and Its Potential for Drug Releasing Coatings

M Müller, M Wöltje, M Hofmaier, B Tarpara… - Langmuir, 2024 - ACS Publications
Dynamic attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy at
both solutions and coatings of a semicrystalline silk material derived from Bombyx mori was …

Splicing Modulators Are Involved in Human Polyglutamine Diversification via Protein Complexes Shuttling between Nucleus and Cytoplasm

MK Shimada - International journal of molecular sciences, 2023 - mdpi.com
Length polymorphisms of polyglutamine (polyQs) in triplet-repeat-disease-causing genes
have diversified during primate evolution despite them conferring a risk of human-specific …

Self-Assembly and Structure Formation of Spider Silk Based Proteins in (Ultra) thin Films

M Hofmaier - 2024 - tud.qucosa.de
Abstract (EN) Spider silk is one of the most fascinating materials found in nature. Besides its
properties like biodegradability, low immunoreactivity, and biocompatibility, especially the …