Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Water in nanopores and biological channels: a molecular simulation perspective

CI Lynch, S Rao, MSP Sansom - Chemical reviews, 2020 - ACS Publications
This Review explores the dynamic behavior of water within nanopores and biological
channels in lipid bilayer membranes. We focus on molecular simulation studies, alongside …

Cancer biomarker detection: recent achievements and challenges

L Wu, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
The early detection of cancer can significantly reduce cancer mortality and saves lives. Thus,
a great deal of effort has been devoted to the exploration of new technologies to detect early …

Nanopore sensing

W Shi, AK Friedman, LA Baker - Analytical chemistry, 2017 - ACS Publications
Scope of the Review. Herein, we provide an up-to-date overview of the field of nanopore
sensing with emphases placed on the advances made in the most recent two years (2014 …

Nanopore-based fourth-generation DNA sequencing technology

Y Feng, Y Zhang, C Ying, D Wang… - Genomics, Proteomics …, 2015 - academic.oup.com
Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have
the potential to quickly and reliably sequence the entire human genome for less than 1000 …

Nanopores: synergy from DNA sequencing to industrial filtration–small holes with big impact

ZS Siwy, ML Bruening, S Howorka - Chemical Society Reviews, 2023 - pubs.rsc.org
Nanopores in thin membranes play important roles in science and industry. Single
nanopores have provided a step-change in portable DNA sequencing and understanding …

Evolution of plant genome architecture

JF Wendel, SA Jackson, BC Meyers, RA Wing - Genome biology, 2016 - Springer
We have witnessed an explosion in our understanding of the evolution and structure of plant
genomes in recent years. Here, we highlight three important emergent realizations:(1) that …

[图书][B] Solid-state nanopore sensors for nucleic acid analysis

BM Venkatesan, R Bashir - 2011 - Springer
Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Building membrane nanopores

S Howorka - Nature nanotechnology, 2017 - nature.com
Membrane nanopores—hollow nanoscale barrels that puncture biological or synthetic
membranes—have become powerful tools in chemical-and biosensing, and have achieved …

A window into third-generation sequencing

EE Schadt, S Turner, A Kasarskis - Human molecular genetics, 2010 - academic.oup.com
First-and second-generation sequencing technologies have led the way in revolutionizing
the field of genomics and beyond, motivating an astonishing number of scientific advances …