The management of perioperative bleeding involves multiple assessments and strategies to
ensure appropriate patient care. Initially, it is important to identify those patients with an …

ABSTRACT von Willebrand disease (VWD) is the most common inherited bleeding disorder
and arises from deficiencies and/or defects in the plasma protein von Willebrand factor …

Von Willebrand disease (VWD) is a bleeding disorder that is mainly caused by mutations in
the multimeric protein von Willebrand factor (VWF). These mutations may lead to …

Analyses of the bleeding tendency by means of the bleeding score (BS) have been
proposed until now to confirm diagnosis but not to predict clinical outcomes in patients with …

Introduction Although hereditary von Willebrand disease (VWD) is the most common
bleeding disorder, its epidemiology is not well understood. A systematic review …

Introduction von Willebrand disease (VWD), reportedly the most common bleeding disorder,
arises from deficiency and/or defects of von Willebrand factor (VWF). Assessment requires a …

The diagnosis of von Willebrand disease (VWD) remains difficult in a significant proportion
of patients. A Spanish multicentre study investigated a cohort of 556 patients from 330 …

Background There is a lack of prospective clinical trials specifically designed to evaluate the
benefits of prophylaxis with vWF/FVIII concentrates in patients with inherited von Willebrand …

Abstract von Willebrand disease (VWD) type 2 is caused by qualitative abnormalities of von
Willebrand factor (VWF). This study aimed to determine the genotypic and phenotypic …

Patients with congenital bleeding disorders (CBD) in Italy are regularly followed by 52
Haemophilia Treatment Centres (HTCs) distributed throughout the country1. The expertise …