Artificial intelligence in histopathology: enhancing cancer research and clinical oncology

A Shmatko, N Ghaffari Laleh, M Gerstung, JN Kather - Nature cancer, 2022 - nature.com
Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative
information from digital histopathology images. AI is expected to reduce workload for human …

Artificial intelligence to identify genetic alterations in conventional histopathology

D Cifci, S Foersch, JN Kather - The Journal of Pathology, 2022 - Wiley Online Library
Precision oncology relies on the identification of targetable molecular alterations in tumor
tissues. In many tumor types, a limited set of molecular tests is currently part of standard …

Multistain deep learning for prediction of prognosis and therapy response in colorectal cancer

S Foersch, C Glasner, AC Woerl, M Eckstein… - Nature medicine, 2023 - nature.com
Although it has long been known that the immune cell composition has a strong prognostic
and predictive value in colorectal cancer (CRC), scoring systems such as the immunoscore …

Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology

NG Laleh, HS Muti, CML Loeffler, A Echle… - Medical image …, 2022 - Elsevier
Artificial intelligence (AI) can extract visual information from histopathological slides and
yield biological insight and clinical biomarkers. Whole slide images are cut into thousands of …

Adversarial attacks and adversarial robustness in computational pathology

N Ghaffari Laleh, D Truhn, GP Veldhuizen… - Nature …, 2022 - nature.com
Artificial Intelligence (AI) can support diagnostic workflows in oncology by aiding diagnosis
and providing biomarkers directly from routine pathology slides. However, AI applications …

Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study

JM Niehues, P Quirke, NP West, HI Grabsch… - Cell reports …, 2023 - cell.com
Deep learning (DL) can predict microsatellite instability (MSI) from routine histopathology
slides of colorectal cancer (CRC). However, it is unclear whether DL can also predict other …

Deep learning on histopathological images for colorectal cancer diagnosis: a systematic review

A Davri, E Birbas, T Kanavos, G Ntritsos, N Giannakeas… - Diagnostics, 2022 - mdpi.com
Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men, with an increasing incidence. Pathology diagnosis complemented with …

Utility of artificial intelligence with deep learning of hematoxylin and eosin-stained whole slide images to predict lymph node metastasis in T1 colorectal cancer using …

JH Song, Y Hong, ER Kim, SH Kim, I Sohn - Journal of Gastroenterology, 2022 - Springer
Background When endoscopically resected specimens of early colorectal cancer (CRC)
show high-risk features, surgery should be performed based on current guidelines because …

One label is all you need: Interpretable AI-enhanced histopathology for oncology

TE Tavolara, Z Su, MN Gurcan, MKK Niazi - Seminars in Cancer Biology, 2023 - Elsevier
Artificial Intelligence (AI)-enhanced histopathology presents unprecedented opportunities to
benefit oncology through interpretable methods that require only one overall label per …

A review and comparative study of cancer detection using machine learning: SBERT and SimCSE application

M Mokoatle, V Marivate, D Mapiye, R Bornman… - BMC …, 2023 - Springer
Background Using visual, biological, and electronic health records data as the sole input
source, pretrained convolutional neural networks and conventional machine learning …