Potential resistance of SARS-CoV-2 main protease (Mpro) against protease inhibitors: lessons learned from HIV-1 protease
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
Transmitted drug resistance to antiretroviral drugs in Spain during the period 2019–2021
L Viñuela, A De Salazar, A Fuentes… - Journal of Medical …, 2023 - Wiley Online Library
To evaluate the prevalence of transmitted drug resistance (TDR) to nucleoside and
nonnucleoside reverse transcriptase inhibitors (NRTI, NNRTI), protease inhibitors (PI), and …
nonnucleoside reverse transcriptase inhibitors (NRTI, NNRTI), protease inhibitors (PI), and …
[HTML][HTML] Increased prevalence of pretreatment drug resistance mutations in treatment-naïve people living with HIV-1 in Henan Province, China (2022/23)
J Liu, C Liu, Y Wang, S Wei, J Ma, Y Li, X Chen… - Infection, Genetics and …, 2023 - Elsevier
Human deficiency virus type 1 (HIV-1) harboring drug resistance mutations (DRMs) before
the initiation of antiretroviral therapy (ART) poses a serious threat to the efficacy of current …
the initiation of antiretroviral therapy (ART) poses a serious threat to the efficacy of current …
Different mutation tolerance of Lentiviral (HIV-1) and deltaretroviral (BLV and HTLV) protease precursors
The bovine leukemia virus (BLV) and the human T-lymphothropic viruses (HTLVs) are
members of the deltaretrovirus genus of Retroviridae family. An essential event of the …
members of the deltaretrovirus genus of Retroviridae family. An essential event of the …
Prevalence and evolution of transmitted human immunodeficiency virus drug resistance in Belgium between 2013 and 2019
V Mortier, L Debaisieux, G Dessilly… - Open forum …, 2022 - academic.oup.com
Background To assess the prevalence and evolution of transmitted drug resistance (TDR) in
Belgium, a total of 3708 baseline human immunodeficiency virus (HIV)-1 polymerase …
Belgium, a total of 3708 baseline human immunodeficiency virus (HIV)-1 polymerase …
Prevalence of resistance mutations associated with integrase inhibitors in therapy-naive HIV-positive patients in Hungary
É Áy, Á Pocskay, B Lakatos, J Szlávik… - Acta Microbiologica et …, 2021 - akjournals.com
Widespread introduction of HIV integrase inhibitors into clinical care may result in
appearance of drug resistance mutations affecting treatment outcome. The aim of our study …
appearance of drug resistance mutations affecting treatment outcome. The aim of our study …
Comparative Evaluation of Bioinformatic Pipelines for Full-Length Viral Genome Assembly
The increasingly widespread application of next-generation sequencing (NGS) in clinical
diagnostics and epidemiological research has generated a demand for robust, fast …
diagnostics and epidemiological research has generated a demand for robust, fast …
Prevalence of HIV Transmitted Drug Resistance in Nanjing from 2018 to 2021
Y Su, M Qi, M Zhong, N Yu, C Chen, Z Ye… - Infection and Drug …, 2023 - Taylor & Francis
Background Transmitted drug resistance (TDR) is a major challenge in the clinical
management of acquired immunodeficiency syndrome (AIDS). Therefore, this study aimed to …
management of acquired immunodeficiency syndrome (AIDS). Therefore, this study aimed to …