Eosinophils are bone marrow-derived granulocytes that, under homeostatic conditions,
account for as much as 1-3% of peripheral blood leukocytes. During inflammation …

The term osteoimmunology describes an interdisciplinary research field that links the
investigation of osteology (bone cells) with immunology. The crosstalk between innate and …

Rheumatoid arthritis (RA) is an autoimmune disorder that has been associated with the gut
microbiota. However, whether and how the gut microbiota plays a pathogenic role in RA …

Fibroblasts are important regulators of inflammation, but whether fibroblasts change
phenotype during resolution of inflammation is not clear. Here we use positron emission …

Eosinophils are involved in tissue homeostasis. Herein, we unveiled eosinophils as
important regulators of bone homeostasis. Eosinophils are localized in proximity to bone …

Over the past years, eosinophils have become a focus of scientific interest, especially in the
context of their recently uncovered functions (eg antiviral, anti‐inflammatory, regulatory) …

For many oncological conditions, the application of timely and patient-tailored targeted
therapies, or precision medicine, is a major therapeutic development that has provided …

Eosinophils are typically considered tissue-damaging effector cells in type 2 immune-related
diseases. However, they are also increasingly recognized as important modulators of …

Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a
plethora of responses ranging from regulation of tissue homeostasis to host defense and …

Although previous RNA sequencing methods have been widely used in orthopedic research
and have provided ideas for therapeutic strategies, the specific mechanisms of some …