[HTML][HTML] Novel arylazo nicotinate derivatives as effective antibacterial agents: Green synthesis, molecular modeling, and structure-activity relationship studies

MR Eletmany, MA Albalawi, RAK Alharbi… - Journal of Saudi …, 2023 - Elsevier
A series of novel arylazo nicotinates compounds, denoted as (3a-k and 5a-d) were
synthesized and characterized through the reaction of 3-oxo-arylhydrazonals with various …

Green methodologies in organic synthesis: recent developments in our laboratories

EAA Hafez, SM Al-Mousawi, MS Moustafa… - … Chemistry Letters and …, 2013 - Taylor & Francis
The results of the studies carried out in our laboratories during the last 15 years, aimed at
developing green methodologies for the synthesis of polyfunctionalized heteroaromatic …

Molecular docking simulation and anticancer assessment on human breast carcinoma cell line using novel bis (1, 4-dihydropyrano [2, 3-c] pyrazole-5-carbonitrile) and …

SK Salama, MF Mohamed, AF Darweesh… - Bioorganic …, 2017 - Elsevier
An efficient route for the synthesis of novel bis (1, 4-dihydropyrano [2, 3-c] pyrazole-5-
carbonitrile) derivatives is reported. The synthetic pathway involves one pot, synthesis of bis …

Recent developments in pyridazine and condensed pyridazine synthesis

MH Elnagdi, NA Al-Awadi, IA Abdelhamid - Advances in Heterocyclic …, 2009 - Elsevier
Publisher Summary This chapter discusses recent developments in pyridazine and
condensed pyridazine synthesis. Today, the pyridazine nucleus and its 3-oxo derivatives …

Synthesis and Anti‐influenza Virus Activity of Novel bis(4H‐chromene‐3‐carbonitrile) Derivatives

AM Abdella, Y Moatasim, MA Ali… - Journal of …, 2017 - Wiley Online Library
An efficient and convenient method for the synthesis of bis (4H‐chromene‐3‐carbonitrile)
derivatives by one‐pot, multicomponent reaction of bis‐aldehydes, malononitrile, and …

Cytotoxic and Antimicrobial Evaluations of Novel Apoptotic and Anti‐Angiogenic Spiro Cyclic 2‐Oxindole Derivatives of 2‐Amino‐tetrahydroquinolin‐5‐one

SAS Ghozlan, MF Mohamed, AG Ahmed… - Archiv der …, 2015 - Wiley Online Library
A novel series of cyclic 2‐oxindole derivatives incorporating 2‐amino‐tetrahydroquinolin‐5‐
one were prepared. The structures of the prepared compounds were elucidated using …

Microwave Assisted Green Multicomponent Synthesis of Novel bis(2‐Amino‐tetrahydro‐4H‐chromene‐3‐carbonitrile) Derivatives Using Chitosan as Eco‐friendly …

SK Salama, AF Darweesh… - Journal of …, 2017 - Wiley Online Library
A simple, efficient, and eco‐friendly procedure has been developed for the synthesis of bis
(4H‐chromene‐3‐carbonitrile) derivatives using chitosan as catalyst under microwave …

Synthesis, characterization and antitumor activity of novel tetrapodal 1, 4-dihydropyridines: p53 induction, cell cycle arrest and low damage effect on normal cells …

MF Mohamed, AF Darweesh, AHM Elwahy… - RSC …, 2016 - pubs.rsc.org
Synthesis of novel tetrakis (2, 6-dimethyl-4-phenyl-1, 4-dihydropyridinyl) methanes 5a–d by
acid-catalyzed condensation of the tetrakis-aldehydes 6a–d with eight equivalents of 3 …

Regioselective synthesis and theoretical studies of novel bis(tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-ones) catalyzed by ZnO nanoparticles

NAA El-Fatah, AF Darweesh, AA Mohamed… - Monatshefte für Chemie …, 2017 - Springer
A novel series of bis (tetrahydro [1, 2, 4] triazolo [5, 1-b] quinazolin-8 (4 H)-ones) were
prepared in a regioselective manner via a three component reaction of bis-aldehydes with 5 …

[PDF][PDF] Enamines as precursors to polyfunctional heteroaromatic compounds; a decade of development

SM Riyadh, IA Abdelhamid, HM Al-Matar… - …, 2008 - triggered.edina.clockss.org
Recent synthesis and utilization of enamines as precursors for heterocyclic and carbocyclic
compounds are reviewed. Two general synthetic routes for preparation of enamines based …