Since the isolation of HIV, multiple transmissions are thought to have occurred between man
and other old-world primates. Assessment of samples from apes and human beings with …

Analysis of HIV drug resistance has identified sites on HIV target genes that convey
resistance to particular classes of agents. These data may be especially important in …

During the rapid spread of HIV-1 in humans, the main (M) group of HIV-1 has evolved into
ten distinct subtypes, undergone countless recombination events and diversified …

The picture of HIV-1 genetic diversity in the global pandemic continues to evolve.
Identification of new variants, including circulating and unique recombinant forms …

One of the major characteristics of HIV-1 is its high genetic variability and extensive
heterogeneity. This characteristic is due to its molecular traits, which in turn allows it to vary …

The devastating consequences of AIDS pandemic will probably only be controlled when a
vaccine is developed that is safe, effective, affordable, and simple enough to permit …

Most of the current knowledge on antiretroviral (ARV) drug development and resistance is
based on the study of subtype B of HIV-1, which only accounts for 10% of the worldwide HIV …

HIV appears to have diverged into several lineages upon multiple zoonotic introductions
from the nonhuman primates. The HIV-2 and HIV-1 groups M, N, and O likely represent …

Human immunodeficiency virus type 1 (HIV-1) subtype C is the dominant subtype globally,
due largely to the incidence of subtype C infections in sub-Saharan Africa and east Asia. We …

The vast majority of reports on drug resistance deal with subtype B infections in developed
countries, and this is largely due to historical delays in access to antiretroviral therapy (ART) …