Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design
G Bahr, LJ Gonzalez, AJ Vila - Chemical reviews, 2021 - ACS Publications
Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …
spread of genes coding for resistance determinants among bacteria challenges the use of …
Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and …
JC Frisvad, LLH Møller, TO Larsen, R Kumar… - Applied Microbiology …, 2018 - Springer
This review presents an update on the current knowledge of the secondary metabolite
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi
Basidiomycota (basidiomycetes) make up 32% of the described fungi and include most
wood-decaying species, as well as pathogens and mutualistic symbionts. Wood-decaying …
wood-decaying species, as well as pathogens and mutualistic symbionts. Wood-decaying …
Biosynthesis of fungal meroterpenoids
Covering: up to September 2015 Meroterpenoids are hybrid natural products that partially
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …
Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis
RF Little, C Hertweck - Natural Product Reports, 2022 - pubs.rsc.org
Review covering up to mid-2021 The structure of polyketide and non-ribosomal peptide
natural products is strongly influenced by how they are released from their biosynthetic …
natural products is strongly influenced by how they are released from their biosynthetic …
[HTML][HTML] Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity
X Meng, Y Fang, M Ding, Y Zhang, K Jia, Z Li… - Biotechnology …, 2022 - Elsevier
Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …
notably for therapeutic agent development. Genome sequencing revealed that the number …
Genetic platforms for heterologous expression of microbial natural products
Covering: 2005 up to 2019 Natural products are of paramount importance in human
medicine. Not only are most antibacterial and anticancer drugs derived directly from or …
medicine. Not only are most antibacterial and anticancer drugs derived directly from or …
Navigating the fungal polyketide chemical space: from genes to molecules
The iterative type I polyketide synthases (IPKSs) are central to the biosynthesis of an
enormously diverse array of natural products in fungi. These natural products, known as …
enormously diverse array of natural products in fungi. These natural products, known as …
An efficient system for heterologous expression of secondary metabolite genes in Aspergillus nidulans
Fungal secondary metabolites (SMs) are an important source of medically valuable
compounds. Genome projects have revealed that fungi have many SM biosynthetic gene …
compounds. Genome projects have revealed that fungi have many SM biosynthetic gene …
Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger
L Song, JP Ouedraogo, M Kolbusz, TTM Nguyen… - PloS one, 2018 - journals.plos.org
As a powerful tool for fast and precise genome editing, the CRISPR/Cas9 system has been
applied in filamentous fungi to improve the efficiency of genome alteration. However, the …
applied in filamentous fungi to improve the efficiency of genome alteration. However, the …