Neonatal hyperbilirubinemia management: Clinical assessment of bilirubin production

L Du, X Ma, X Shen, Y Bao, L Chen, VK Bhutani - Seminars In Perinatology, 2021 - Elsevier
The predominant cause of elevated total/plasma bilirubin (TB) levels is from an increase in
bilirubin production primarily because of ongoing hemolysis. If undiagnosed or untreated …

Heme catabolism by tumor-associated macrophages controls metastasis formation

FM Consonni, A Bleve, MG Totaro, M Storto… - Nature …, 2021 - nature.com
Although the pathological significance of tumor-associated macrophage (TAM)
heterogeneity is still poorly understood, TAM reprogramming is viewed as a promising …

The role of gasotransmitters in neonatal physiology

T Liu, GT Mukosera, AB Blood - Nitric Oxide, 2020 - Elsevier
The gasotransmitters, nitric oxide (NO), hydrogen sulfide (H 2 S), and carbon monoxide
(CO), are endogenously-produced volatile molecules that perform signaling functions …

Hemolysis during and after 21 days of head‐down‐tilt bed rest

G Trudel, HK Uhthoff, O Laneuville - Physiological Reports, 2017 - Wiley Online Library
Hemoconcentration is observed in bed rest studies, descent from altitude, and exposure to
microgravity. Hemoconcentration triggers erythrocyte losses to subsequently normalize …

Higher ETCOc predicts longer phototherapy treatment in neonatal hyperbilirubinemia

YL Zhan, HB Peng, ZC Jin, JF Su, XY Tan… - Frontiers in …, 2023 - frontiersin.org
Objective This study aimed to evaluate the predictive performance of end-tidal carbon
monoxide corrected to ambient carbon monoxide (ETCOc) values phototherapy in neonates …

Carboxyhaemoglobin levels and free-radical-related diseases in prematurely born infants

N Bednarczuk, EE Williams, A Greenough… - Early Human …, 2022 - Elsevier
Abstract Background Carboxyhaemoglobin (COHb) levels may reflect the level of early
oxidative stress which plays a role in mediating free-radical-related diseases in prematurely …

[HTML][HTML] Carboxyhemoglobin levels in preterm neonatal late-onset sepsis: to predict or not to predict

G Vardar, E Ozek - … Journal of Hematology and Infectious Diseases, 2023 - ncbi.nlm.nih.gov
Background In this study, we aimed to evaluate carboxyhemoglobin (COHb) levels in
diagnosing late-onset sepsis (LOS) in preterm neonates. Methods The records of culture …

Arterial carboxyhaemoglobin levels in children admitted to PICU: a retrospective observational study

A Chawla, S Ray, A Matettore, MJ Peters - PLoS One, 2019 - journals.plos.org
While carbon monoxide (CO) is considered toxic, low levels of endogenously produced CO
are protective against cellular injury induced by oxidative stress. Carboxyhaemoglobin …

Carboxyhemoglobin levels in children during extracorporeal membrane oxygenation support: a retrospective study

S Kimura, B Gelbart, R Chiletti, D Stephens… - Perfusion, 2022 - journals.sagepub.com
Introduction: Hemolysis is a common complication of extracorporeal membrane oxygenation
(ECMO). There are few data on whether carboxyhemoglobin (COHb), a potential marker of …

Endogenous Carboxyhemoglobin Level Variation in COVID-19 and Bacterial Sepsis: A Novel Approach?

BL Grigorescu, I Săplăcan, IR Bordea, M Petrisor… - Microorganisms, 2022 - mdpi.com
Background: The increased production of carbon monoxide (CO) in sepsis has been proven,
but the blood level variations of carboxyhemoglobin (COHb) as a potential evolutionary …