Locomotor behaviors are critical for survival and enable animals to navigate their
environment, find food and evade predators. The circuits in the brain and spinal cord that …

Vertebrate skeletal muscle is composed of distinct types of fibre that are functionally adapted
through differences in their physiological and metabolic properties. An understanding of the …

Zebrafish have recently emerged as an attractive in vivo model for epilepsy. Seven-day-old
zebrafish larvae exposed to the GABAA antagonist pentylenetetrazol (PTZ) exhibit increased …

Abstract Febrile seizures affect 2–4% of all children and have a strong genetic component.
Recurrent mutations in three main genes (SCN1A, SCN1B and GABRG2),, have been …

Zebrafish embryos and early larvae are becoming increasingly important as models in
biomedical research because of their low cost, high throughput and potential as a …

Phenomenal consciousness or the subjective experience of feeling sensory stimuli is
fundamental to human existence. Because of the ubiquity of their subjective experiences …

In the vertebrate spinal cord, cerebrospinal fluid-contacting neurons (CSF-cNs) are
GABAergic neurons whose functions are only beginning to unfold. Recent evidence …

Vertebrate movement is orchestrated by spinal inter-and motor neurons that, together with
sensory and cognitive input, produce dynamic motor behaviors. These behaviors vary from …

The sense of touch allows an organism to detect and respond to physical environmental
stimuli. Mechanosensitive proteins play a crucial role in this process by converting the …

Despite numerous physiological studies about reflexes in the spinal cord, the contribution of
mechanosensory feedback to active locomotion and the nature of underlying spinal circuits …