Major roles of isocitrate lyase and malate synthase in bacterial and fungal pathogenesis

MF Dunn, JA Ramirez-Trujillo… - …, 2009 - microbiologyresearch.org
The glyoxylate cycle is an anaplerotic pathway of the tricarboxylic acid (TCA) cycle that
allows growth on C2 compounds by bypassing the CO2-generating steps of the TCA cycle …

The glyoxylate cycle and alternative carbon metabolism as metabolic adaptation strategies of Candida glabrata: perspectives from Candida albicans and …

SY Chew, WJY Chee, LTL Than - Journal of biomedical science, 2019 - Springer
Background Carbon utilization and metabolism are fundamental to every living organism for
cellular growth. For intracellular human fungal pathogens such as Candida glabrata, an …

Cr(VI) Reduction and Fe(II) Regeneration by Penicillium oxalicum SL2-Enhanced Nanoscale Zero-Valent Iron

Y Luo, J Pang, C Peng, J Ye, B Long… - … Science & Technology, 2023 - ACS Publications
Nanoscale zero-valent iron (nZVI) faces significant challenges in Cr (VI) remediation through
aggregation and passivation. This study identified a Cr (VI)-resistant filamentous fungus …

Paracoccidioides Species Complex: Ecology, Phylogeny, Sexual Reproduction, and Virulence

MM Teixeira, RC Theodoro, G Nino-Vega… - PLoS …, 2014 - journals.plos.org
Paracoccidioidomycosis (PCM) is a deep systemic mycosis caused by human fungal
pathogens of the Paracoccidioides genus. The disease is geographically restricted to …

Multiple alternative carbon pathways combine to promote Candida albicans stress resistance, immune interactions, and virulence

RB Williams, MC Lorenz - MBio, 2020 - Am Soc Microbiol
The phagocytic cells of the innate immune system are an essential first line of antimicrobial
defense, and yet Candida albicans, one of the most problematic fungal pathogens, is …

Autophagy supports Candida glabrata survival during phagocytosis

A Roetzer, N Gratz, P Kovarik… - Cellular …, 2010 - Wiley Online Library
The opportunistic human fungal pathogen Candida glabrata is confronted with phagocytic
cells of the host defence system. Survival of internalized cells is thought to contribute to …

The future of antifungal drug therapy: novel compounds and targets

C Mota Fernandes, D Dasilva… - Antimicrobial agents …, 2021 - Am Soc Microbiol
Fungal infections are a universal problem and are routinely associated with high morbidity
and mortality rates in immunocompromised patients. Existing therapies comprise five …

Genes Differentially Expressed in Conidia and Hyphae of Aspergillus fumigatus upon Exposure to Human Neutrophils

JA Sugui, HS Kim, KA Zarember, YC Chang, JI Gallin… - PLoS …, 2008 - journals.plos.org
Background Aspergillus fumigatus is the most common etiologic agent of invasive
aspergillosis in immunocompromised patients. Several studies have addressed the …

The transcriptional response of Cryptococcus neoformans to ingestion by Acanthamoeba castellanii and macrophages provides insights into the evolutionary …

LS Derengowski, HC Paes, P Albuquerque… - Eukaryotic …, 2013 - Am Soc Microbiol
Virulence of Cryptococcus neoformans for mammals, and in particular its intracellular style,
was proposed to emerge from evolutionary pressures on its natural environment by …

Paracoccidioides Spp.: Virulence Factors and Immune‐Evasion Strategies

E Camacho, GA Niño-Vega - Mediators of inflammation, 2017 - Wiley Online Library
Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most
relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact …