CONTEXT: Prostate cancer (PCa) remains an increasingly common malignancy worldwide.
The optimal management of clinically localized, early-stage disease remains unknown, and …

Context The notion of insignificant prostate cancer (Ins-PCa) has progressively emerged in
the past two decades. The clinical relevance of such a definition was based on the fact that …

BACKGROUND: Overdiagnosis and subsequent overtreatment are important side effects of
screening for, and early detection of, prostate cancer (PCa). Active surveillance (AS) is of …

Importance Men with prostate cancer who are undergoing active surveillance are at an
increased risk of cardiovascular death and disease progression. Exercise has been shown …

Purpose We assessed outcomes of men with prostate cancer enrolled in active surveillance.
Patients and Methods Since 1995, a total of 769 men diagnosed with prostate cancer have …

Prostate cancer has surpassed lung cancer as the most common cancer in men in the
United States. The NCCN Guidelines for Prostate Cancer provide multidisciplinary …

Purpose To investigate whether apparent diffusion coefficients (ADCs) derived from diffusion-
weighted (DW) magnetic resonance (MR) imaging at 3 T correlate with the clinical risk of …

Purpose: Targeted biopsy of lesions identified on magnetic resonance imaging may
enhance the detection of clinically relevant prostate cancers. We evaluated prostate cancer …

Methods: A literature search of MEDLINE, EMBASE, the Cochrane library, guideline
databases and relevant meeting proceedings was performed and a systematic review of …

Objective To modify the Prostate Cancer Prevention Trial risk calculator (PCPTRC) to predict
low-vs high-grade (Gleason grade≥ 7) prostate cancer and incorporate percent free …