Antioxidant therapies in traumatic brain injury

V Di Pietro, KM Yakoub, G Caruso, G Lazzarino… - Antioxidants, 2020 - mdpi.com
Due to a multiplicity of causes provoking traumatic brain injury (TBI), TBI is a highly
heterogeneous pathology, characterized by high mortality and disability rates. TBI is an …

[HTML][HTML] An updated review on the versatile role of chrysin in neurological diseases: Chemistry, pharmacology, and drug delivery approaches

M Talebi, M Talebi, T Farkhondeh… - Biomedicine & …, 2021 - Elsevier
Neurological diseases are responsible for a large number of morbidities and mortalities in
the world. Flavonoids are phytochemicals that possess various health-promoting impacts …

Neuroprotective potential of chrysin: Mechanistic insights and therapeutic potential for neurological disorders

A Mishra, PS Mishra, R Bandopadhyay, N Khurana… - Molecules, 2021 - mdpi.com
Chrysin, a herbal bioactive molecule, exerts a plethora of pharmacological effects, including
anti-oxidant, anti-inflammatory, neuroprotective, and anti-cancer. A growing body of …

Antioxidant therapies in traumatic brain injury

CK Davis, R Vemuganti - Neurochemistry international, 2022 - Elsevier
Oxidative stress plays a crucial role in traumatic brain injury (TBI) pathogenesis. Reactive
oxygen species (ROS) and reactive nitrogen species (RNS) formed in excess after TBI …

Sex-based differences of antioxidant enzyme nanoparticle effects following traumatic brain injury

AW Tarudji, HA Miller, ET Curtis, CL Porter… - Journal of Controlled …, 2023 - Elsevier
Following traumatic brain injury (TBI), reactive oxygen species (ROS) are released in
excess, causing oxidative stress, carbonyl stress, and cell death, which induce the additional …

Neuroprotective effect of chrysin on isoniazid-induced neurotoxicity via suppression of oxidative stress, inflammation and apoptosis in rats

H Çelik, S Kucukler, S Çomaklı, C Caglayan… - Neurotoxicology, 2020 - Elsevier
Isoniazid (INH) is among the most important anti-tuberculosis agents widely prescribed.
However, its clinical use is restricted due to its severe side effects associated with …

Chrysin protects against memory and hippocampal neurogenesis depletion in D-galactose-induced aging in rats

R Prajit, N Sritawan, K Suwannakot, S Naewla… - Nutrients, 2020 - mdpi.com
The interruption of hippocampal neurogenesis due to aging impairs memory. The
accumulation of D-galactose (D-gal), a monosaccharide, induces brain aging by causing …

Chrysin reduces inflammation and oxidative stress and improves ovarian function in D-gal-induced premature ovarian failure

X Li, X Li, L Deng - Bioengineered, 2022 - Taylor & Francis
Premature ovarian failure (POF), a frequently occurring pathology. Chrysin has antioxidant,
anti-inflammatory, anti-apoptotic and other pharmacological activities. This study was …

Chrysin mitigates bleomycin-induced pulmonary fibrosis in rats through regulating inflammation, oxidative stress, and hypoxia

MO Kseibati, MH Sharawy, HA Salem - International immunopharmacology, 2020 - Elsevier
Pulmonary fibrosis is a chronic condition characterized by fibroblast proliferation, and the
infiltration of inflammatory cells that can initiate local tissue hypoxia. In this study the effect of …

Dietary (poly) phenols in traumatic brain injury

R Carecho, D Carregosa, BO Ratilal, I Figueira… - International Journal of …, 2023 - mdpi.com
Traumatic brain injury (TBI) remains one of the leading causes of death and disability in
young adults worldwide. Despite growing evidence and advances in our knowledge …