Background Recently, a variety of clinical trials have shown that apatinib, a small-molecule
anti-angiogenic drug, exerts promising inhibitory effects on multiple solid tumors, including …

The cancer metabolic reprogramming allows the maintenance of tumor proliferation,
expansion and survival by altering key bioenergetics, biosynthetic and redox functions to …

Metabolic reprogramming, carried out by cancer cells to rapidly adapt to stress such as
hypoxia and limited nutrient conditions, is an emerging concepts in tumor biology, and is …

Acute myeloid leukemia (AML) remains a clinical challenge due to frequent chemotherapy
resistance and deadly relapses. We are exploring the immunotherapeutic potential of …

Acute myeloid leukemia (AML) is an aggressive haematological malignancy characterized
by highly proliferative accumulation of immature and dysfunctional myeloid cells. Quercetin …

Acute myeloid leukemia (AML) is a hematological malignancy with a low cure rate,
especially in the elderly. Previous studies have shown that long non-coding RNA (lncRNA) …

The treatment of bladder cancer has recently shown minimal progress. Gene therapy
mediated by CRISPR provides a new option for bladder cancer treatment. In this study, we …

Flavonoids are ubiquitous groups of polyphenolic compounds present in most natural
products and plants. These substances have been shown to have promising …

Chemotherapy-resistant cancer recurrence is a major cause of mortality. In acute myeloid
leukemia (AML), chemorefractory relapses result from the complex interplay between altered …

Purpose As the deadliest gynecological malignancy, ovarian cancer ranks as a major cause
of disease-related deaths to women worldwide and is treated with transurethral resection or …