Vertical nanowire array-based biosensors: device design strategies and biomedical applications
Biosensors have been extensively studied in the areas of biology, electronics, chemistry,
biotechnology, medicine, and various engineering fields. The interdisciplinarity creates an …
biotechnology, medicine, and various engineering fields. The interdisciplinarity creates an …
Toward brain-on-a-chip: Human induced pluripotent stem cell-derived guided neuronal networks in tailor-made 3D nanoprinted microscaffolds
Brain-on-a-chip (BoC) concepts should consider three-dimensional (3D) scaffolds to mimic
the 3D nature of the human brain not accessible by conventional planar cell culturing …
the 3D nature of the human brain not accessible by conventional planar cell culturing …
Microscaffolds by Direct Laser Writing for Neurite Guidance Leading to Tailor‐Made Neuronal Networks
While modern day integrated electronic circuits are essentially designed in a 2D fashion, the
brain can be regarded as a 3D circuit. The thus enhanced connectivity enables much more …
brain can be regarded as a 3D circuit. The thus enhanced connectivity enables much more …
Label-free, non-contact determination of resting membrane potential using dielectrophoresis
Measurement of cellular resting membrane potential (RMP) is important in understanding
ion channels and their role in regulation of cell function across a wide range of cell types …
ion channels and their role in regulation of cell function across a wide range of cell types …
Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications
Nanostructured substrates such as nanowire arrays form a powerful tool for building next-
generation medical devices. So far, human pluripotent stem cell-derived neurons—a …
generation medical devices. So far, human pluripotent stem cell-derived neurons—a …
Culturing human iPSC-derived neural progenitor cells on nanowire arrays: mapping the impact of nanowire length and array pitch on proliferation, viability, and …
Nanowire arrays used as cell culture substrates build a potent tool for advanced biological
applications such as cargo delivery and biosensing. The unique topography of nanowire …
applications such as cargo delivery and biosensing. The unique topography of nanowire …
Neurite guidance and neuro-caging on steps and grooves in 2.5 dimensions
C Fendler, J Harberts, L Rafeldt, G Loers… - Nanoscale …, 2020 - pubs.rsc.org
Directed guidance of neurites is a pre-requisite for tailor-made designs of interfaces
between cells and semiconducting components. Grayscale lithography, reactive ion etching …
between cells and semiconducting components. Grayscale lithography, reactive ion etching …
Robust neuronal differentiation of human iPSC-derived neural progenitor cells cultured on densely-spaced spiky silicon nanowire arrays
J Harberts, M Siegmund, M Schnelle, T Zhang, Y Lei… - Scientific Reports, 2021 - nature.com
Nanostructured cell culture substrates featuring nanowire (NW) arrays have been applied to
a variety of basic cell lines and rodent neurons to investigate cellular behavior or to stimulate …
a variety of basic cell lines and rodent neurons to investigate cellular behavior or to stimulate …
A temperature-controlled patch clamp platform demonstrated on jurkat T lymphocytes and human induced pluripotent stem cell-derived neurons
Though patch clamping at room temperature is a widely disseminated standard procedure in
the electrophysiological community, it does not represent the biological system in mammals …
the electrophysiological community, it does not represent the biological system in mammals …
Generation of Human iPSC‐Derived Neurons on Nanowire Arrays Featuring Varying Lengths, Pitches, and Diameters
Nanowire (NW) arrays interfaced with biological cells have been demonstrated to be potent
tools for advanced applications such as sensing, stimulation, or drug delivery. Many …
tools for advanced applications such as sensing, stimulation, or drug delivery. Many …