[HTML][HTML] DPPH radical scavenging assay

İ Gulcin, SH Alwasel - Processes, 2023 - mdpi.com
Today, there is an increasing interest in antioxidants, especially to prevent the known
harmful effects of free radicals in human metabolism and their deterioration during …

Antioxidants and antioxidant methods: An updated overview

İ Gulcin - Archives of toxicology, 2020 - Springer
Antioxidants had a growing interest owing to their protective roles in food and
pharmaceutical products against oxidative deterioration and in the body and against …

[HTML][HTML] Metal ions, metal chelators and metal chelating assay as antioxidant method

İ Gulcin, SH Alwasel - Processes, 2022 - mdpi.com
Heavy metals are essential for a wide range of biological processes, including the growth
and reproduction of cells, synthesis of biomolecules, many enzymatic reactions, and the …

[HTML][HTML] Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase

RJ Obaid, N Naeem, EU Mughal, MM Al-Rooqi… - RSC …, 2022 - pubs.rsc.org
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …

Pharmacological significance of nitrogen-containing five and six-membered heterocyclic scaffolds as potent cholinesterase inhibitors for drug discovery

RJ Obaid, EU Mughal, N Naeem, MM Al-Rooqi… - Process …, 2022 - Elsevier
N-heterocycles are crucial due to their biological, chemical, and practical significance. They
are heavily investigated in biological processes involving anticancer, anti-inflammatory …

[HTML][HTML] Microorganisms: a potential source of bioactive molecules for antioxidant applications

A Rani, KC Saini, F Bast, S Mehariya, SK Bhatia… - Molecules, 2021 - mdpi.com
Oxidative stress originates from an elevated intracellular level of free oxygen radicals that
cause lipid peroxidation, protein denaturation, DNA hydroxylation, and apoptosis, ultimately …

[HTML][HTML] A review on recent approaches on molecular docking studies of novel compounds targeting acetylcholinesterase in Alzheimer disease

SC Peitzika, E Pontiki - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …

Novel 2-aminopyridine liganded Pd (II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties

F Erdemir, DB Celepci, A Aktaş, Y Gök, R Kaya… - Bioorganic …, 2019 - Elsevier
In this work, the synthesis, crystal structure, characterization, and enzyme inhibition effects of
the novel a series of 2-aminopyridine liganded Pd (II) N-heterocyclic carbene (NHC) …

[HTML][HTML] Screening of carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzyme inhibition effects and antioxidant activity of …

L Durmaz, A Erturk, M Akyüz, L Polat Kose, EM Uc… - Molecules, 2022 - mdpi.com
Coumestrol (3, 9-dihydroxy-6-benzofuran [3, 2-c] chromenone) as a phytoestrogen and
polyphenolic compound is a member of the Coumestans family and is quite common in …

The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products

C Bayrak, P Taslimi, HS Karaman, I Gulcin… - Bioorganic chemistry, 2019 - Elsevier
Starting from vanillin, known four benzyl bromides with Br were synthesized. The first
synthesis of natural product 3, 4-dibromo-5-((methylsulfonyl) methyl) benzene-1, 2-diol (2) …