TUFT1 regulates metastasis of pancreatic cancer through HIF1-Snail pathway induced epithelial–mesenchymal transition

B Zhou, H Zhan, L Tin, S Liu, J Xu, Y Dong, X Li, L Wu… - Cancer letters, 2016 - Elsevier
Pancreatic cancer (PC) is usually lethal because of late diagnosis and early metastasis.
Analysis of data from online database showed that TUFT1 is highly expressed in liver …

Biomaterial and mesenchymal stem cell for articular cartilage reconstruction

Y Shen, Y Fu, J Wang, G Li, X Zhang… - Current stem cell …, 2014 - benthamdirect.com
Cartilage has poor ability of spontaneous repair. Traditional treatments such as
microfracture, bone drilling and autologous osteochondral graft were not fully satisfactory to …

Boron as boric acid induces mRNA expression of the differentiation factor tuftelin in pre-osteoblastic MC3T3-E1 cells

SS Hakki, SB Bozkurt, EE Hakki, FH Nielsen - Biological Trace Element …, 2021 - Springer
The effects of boron on the formation and maintenance of mineralized structures at the
molecular level are still not clearly defined. Thus, a study was conducted using MC3T3-E1 …

[HTML][HTML] Transcriptomic profiling of Rana [Lithobates] catesbeiana back skin during natural and thyroid hormone-induced metamorphosis under different temperature …

LM Corrie, H Kuecks-Winger, H Ebrahimikondori… - … and Physiology Part D …, 2024 - Elsevier
As amphibians undergo thyroid hormone (TH)-dependent metamorphosis from an aquatic
tadpole to the terrestrial frog, their innate immune system must adapt to the new …

Stress-induced upregulation of VLDL receptor alters Wnt-signaling in neurons

K Kysenius, HJ Huttunen - Experimental cell research, 2016 - Elsevier
Lipoprotein receptor family members hold multiple roles in the brain, and alterations in
lipoprotein receptor expression and function are implicated in neuronal stress …

Tuftelin is required for NGF-induced differentiation of PC12 cells

D Shilo, G Cohen, A Blumenfeld, K Goren… - Journal of Molecular …, 2019 - Springer
Nerve growth factor (NGF) promotes pleiotropic gene transcription-dependent biological
effects, in neuronal and non-neuronal cells, including survival, proliferation, differentiation …

Evolutionary analysis of the mammalian tuftelin sequence reveals features of functional importance

S Delgado, D Deutsch, JY Sire - Journal of molecular evolution, 2017 - Springer
Tuftelin (TUFT1) is an acidic, phosphorylated glycoprotein, initially discovered in developing
enamel matrix. TUFT1 is expressed in many mineralized and non-mineralized tissues. We …

Tuftelin and HIFs expression in osteogenesis

J Bobek, V Oralova, A Kratochvilova, I Zvackova… - Histochemistry and Cell …, 2019 - Springer
Tuftelin was originally discovered and mostly studied in the tooth, but later found also in
other organs. Despite its wide distribution among tissues, tuftelin's function has so far been …

Tuftelin's involvement in embryonic development

D Shilo, A Blumenfeld, A Haze… - … Zoology Part B …, 2019 - Wiley Online Library
Little is known about tuftelin expression in the developing embryo, previously it was thought
to play a role in tooth enamel mineralization. In this study we show tuftelin's spatio‐temporal …

Expresión de tuftelina en gérmenes dentales humanos

PM Campos-Navarro, AL Guerrero-Barrera… - International Journal of …, 2017 - SciELO Chile
La tuftelina es una proteína secretada en la matriz adamantina en desarrollo durante la
formación del esmalte. Su función continúa sin esclarecerse, aunque se presume que juega …