World population growth and aging are posing unprecedented challenges in sustaining the
health of 9.1 billion people that will be occupying the planet by 2050. Although …

Human longevity has increased dramatically during the past century. More than 20% of the 9
billion population of the world will exceed the age of 60 in 2050. Since the last three …

The aim of this review is to shed light over the most recent advances in Coenzyme Q10
(CoQ10) applications as well as to provide detailed information about the functions of this …

Reactive oxygen species (ROS), including superoxide anion, hydrogen peroxide, and
hydroxyl radical, can be formed as normal products of aerobic metabolism and can be …

Two alternative models of organization of the mitochondrial electron transport chain (mETC)
have been alternatively favored or questioned by the accumulation evidences of different …

Coenzyme Q10 is a small electron carrier of the respiratory chain with antioxidant properties,
widely used for the treatment of mitochondrial disorders. Mitochondrial diseases are …

Antioxidant enzymes (AOEs) catalase and superoxide dismutase (SOD) detoxify harmful
reactive oxygen species, but the therapeutic utility of AOEs is hindered by inadequate …

Background Mitochondria are both the cellular powerhouse and the major source of reactive
oxygen species. Coenzyme Q10 plays a key role in mitochondrial energy production and is …

Introduction Statin-associated myalgia occurs in about 1–3% of patients in the medical
literature. Plasma CoQ10 levels are reduced in patients undergoing statin. Objective The …

Objective: Coenzyme Q10 (CoQ10) is an endogenous lipid-soluble benzoquinone
compound that functions as a diffusible electron carrier in the electron transport chain. It is …