Maternal obesity and the impact of associated early-life inflammation on long-term health of offspring

M Denizli, ML Capitano, KL Kua - Frontiers in cellular and infection …, 2022 - frontiersin.org
The prevalence of obesity is increasingly common in the United States, with~ 25% of women
of reproductive age being overweight or obese. Metaflammation, a chronic low grade …

[HTML][HTML] Western diet consumption during development: setting the stage for neurocognitive dysfunction

L Tsan, L Décarie-Spain, EE Noble… - Frontiers in …, 2021 - frontiersin.org
The dietary pattern in industrialized countries has changed substantially over the past
century due to technological advances in agriculture, food processing, storage, marketing …

Effects of early‐life stress on social and anxiety‐like behaviors in adult mice: Sex‐specific effects

NP Bondar, AA Lepeshko… - Behavioural …, 2018 - Wiley Online Library
Stressful events in an early postnatal period have critical implications for the individual's life
and can increase later risk for psychiatric disorders. The aim of this study was to investigate …

Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high-fat diet

M Bordeleau, C Lacabanne… - Journal of …, 2020 - Springer
Background Maternal nutrition is critical for proper fetal development. While increased
nutrient intake is essential during pregnancy, an excessive consumption of certain nutrients …

Relationship of maternal high-fat diet during pregnancy and lactation to offspring health

K Gawlińska, D Gawliński, M Filip… - Nutrition …, 2021 - academic.oup.com
A balanced maternal diet is essential for proper fetal development, and the consumption of a
nutritionally inadequate diet during intrauterine development and early childhood is …

Mechanisms underlying the cognitive and behavioural effects of maternal obesity

K Hasebe, MD Kendig, MJ Morris - Nutrients, 2021 - mdpi.com
The widespread consumption of 'western'-style diets along with sedentary lifestyles has led
to a global epidemic of obesity. Epidemiological, clinical and preclinical evidence suggests …

[HTML][HTML] Maternal dietary patterns are associated with susceptibility to a depressive-like phenotype in rat offspring

K Gawlińska, D Gawliński, M Korostyński… - Developmental …, 2021 - Elsevier
Environmental factors such as maternal diet, determine the pathologies that appear early in
life and can persist in adulthood. Maternally modified diets provided through pregnancy and …

Of 'junk food'and 'brain food': how parental diet influences offspring neurobiology and behaviour

C Bodden, AJ Hannan, AC Reichelt - Trends in Endocrinology & …, 2021 - cell.com
Unhealthy lifestyles and mental health problems are increasingly prevalent globally. Not
only are 'junk food'-induced overweight and obesity risk factors for the development of brain …

Diet-induced modification of the sperm epigenome programs metabolism and behavior

C Bodden, AJ Hannan, AC Reichelt - Trends in Endocrinology & …, 2020 - cell.com
Globally, obesity has reached epidemic proportions. The rapidly increasing numbers of
overweight people can be traced back to overconsumption of energy-dense, poor-quality …

Small cells with big implications: microglia and sex differences in brain development, plasticity and behavioral health

LH Nelson, AI Saulsbery, KM Lenz - Progress in neurobiology, 2019 - Elsevier
Brain sex differences are programmed largely by sex hormone secretions and direct sex
chromosome effects in early life, and are subsequently modulated by early life experiences …