Engineering cells for precision drug delivery: New advances, clinical translation, and emerging strategies

CJ Chao, E Zhang, Z Zhao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Cells have emerged as a promising new form of drug delivery carriers owing to their
distinguished advantages such as naturally bypassing immune recognition, intrinsic …

Cell primitive-based biomimetic functional materials for enhanced cancer therapy

GF Luo, WH Chen, X Zeng, XZ Zhang - Chemical Society Reviews, 2021 - pubs.rsc.org
Cell primitive-based functional materials that combine the advantages of natural substances
and nanotechnology have emerged as attractive therapeutic agents for cancer therapy. Cell …

Advanced strategies to evade the mononuclear phagocyte system clearance of nanomaterials

J Lu, X Gao, S Wang, Y He, X Ma, T Zhang, X Liu - Exploration, 2023 - Wiley Online Library
Nanomaterials are promising carriers to improve the bioavailability and therapeutic
efficiency of drugs by providing preferential drug accumulation at their sites of action, but …

Functional electrospun fibers for local therapy of cancer

J Zhao, W Cui - Advanced Fiber Materials, 2020 - Springer
Despite great efforts and advancement in the treatment of cancer, tumor recurrence and
metastasis remain significant challenges and demand novel therapy strategies. Recently …

Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling

HM Jeon, JY Kim, HJ Cho, WJ Lee, D Nguyen, SS Kim… - Cancer cell, 2023 - cell.com
Radiation therapy (RT) provides therapeutic benefits for patients with glioblastoma (GBM),
but inevitably induces poorly understood global changes in GBM and its microenvironment …

Advances in drug delivery for post-surgical cancer treatment

LL Bu, J Yan, Z Wang, H Ruan, Q Chen, V Gunadhi… - Biomaterials, 2019 - Elsevier
Surgery remains a primary modality of treatment for the majority of solid tumor malignancies.
While advancements in surgical technique and instrumentation have improved the quality of …

Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer

RC Gimple, S Bhargava, D Dixit… - Genes & …, 2019 - genesdev.cshlp.org
Glioblastoma ranks among the most lethal of all human cancers. Glioblastomas display
striking cellular heterogeneity, with stem-like glioblastoma stem cells (GSCs) at the apex …

Biomaterials for personalized cell therapy

AL Facklam, LR Volpatti, DG Anderson - Advanced materials, 2020 - Wiley Online Library
Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …

Mesenchymal stem/stromal cells as next-generation drug delivery vehicles for cancer therapeutics

Y Takayama, K Kusamori… - Expert opinion on drug …, 2021 - Taylor & Francis
Introduction Drug delivery to solid tumors remains a significant therapeutic challenge.
Mesenchymal stem/stromal cells (MSCs) home to tumor tissues and can be employed as …

Cell-based drug delivery systems for biomedical applications

T Li, H Dong, C Zhang, R Mo - Nano Research, 2018 - Springer
Spurred by numerous achievements in nanoscience and nanotechnology, the evolution of
nanoparticulate drug delivery systems (nano-DDSs) is in its rapid growth period and …