Carbonic anhydrase (CA, EC 4.2. 1.1) is a protein that is especially well-suited to serve as a
model in many types of studies in biophysics, bioanalysis, the physical-organic chemistry of …

This review will cover small-angle X-ray scattering of polymers, especially with the use of
synchrotron radiation. By nature, small-angle X-ray scattering (SAXS) probes relatively large …

Pulse field gradient NMR methods have been used to determine the effective hydrodynamic
radii of a range of native and nonnative protein conformations. From these experimental …

Parkinson's disease (PD) is a slowly progressive movement disorder that results from the
loss of dopaminergic neurons in the substantia nigra, a small area of cells in the mid-brain …

The combined effects of concentration and pH on the conformational states of bovine serum
albumin (BSA) are investigated by small-angle x-ray scattering. Serum albumins, at …

Publisher Summary This chapter deals with the structure of the molten globules of various
globular proteins revealed by the recent experimental studies. Recent advances in …

The folding of a polypeptide chain of a relatively large globular protein into its unique three-
dimensional and functionally active structure occurs via folding intermediates. These partly …

The structure and dynamics of two partially folded states of apomyoglobin have been
characterized at equilibrium using multi-dimensional NMR spectroscopy. Residue-specific …

Monitoring the changes in charge-state distributions of protein ions in electrospray ionization
(ESI) mass spectra has become one of the commonly accepted tools to detect large-scale …

To investigate protein folding dynamics in terms of compactness, we developed a
continuous-flow mixing device to make small-angle x-ray scattering measurements with the …