A review of keratoconus: diagnosis, pathophysiology, and genetics

VM Tur, C MacGregor, R Jayaswal, D O'Brart… - Survey of …, 2017 - Elsevier
We discuss new approaches to the early detection of keratoconus and recent investigations
regarding the nature of its pathophysiology. We review the current evidence for its complex …

The genetic and environmental factors for keratoconus

A Gordon-Shaag, M Millodot… - BioMed research …, 2015 - Wiley Online Library
Keratoconus (KC) is the most common cornea ectatic disorder. It is characterized by a cone‐
shaped thin cornea leading to myopia, irregular astigmatism, and vision impairment. It …

Keratoconus: an inflammatory disorder?

V Galvis, T Sherwin, A Tello, J Merayo, R Barrera… - Eye, 2015 - nature.com
Keratoconus has been classically defined as a progressive, non-inflammatory condition,
which produces a thinning and steepening of the cornea. Its pathophysiological …

Eye rubbing in the aetiology of keratoconus: a systematic review and meta-analysis

S Sahebjada, HH Al-Mahrouqi, S Moshegov… - Graefe's Archive for …, 2021 - Springer
Purpose Keratoconus is a potentially blinding condition that slowly deforms the cornea in
young people. Despite the increasing prevalence of keratoconus, the exact aetiology of the …

Pediatric keratoconus: a review of the literature

S Mukhtar, BK Ambati - International ophthalmology, 2018 - Springer
Purpose To describe the epidemiology and prevalence, rates of progression, difference
between adult and pediatric populations, and therapeutic approaches to pediatric …

[HTML][HTML] Updates on managements for keratoconus

M Mohammadpour, Z Heidari, H Hashemi - Journal of current …, 2018 - Elsevier
Purpose Keratoconus is a progressive disease of the cornea which can lead to blindness as
irregular astigmatism increases. Currently, a variety of methods are available for the …

Contact lens management of keratoconus

LE Downie, RG Lindsay - Clinical and Experimental Optometry, 2015 - Taylor & Francis
Contact lenses are the primary form of visual correction for patients with keratoconus.
Contemporary advances in contact lens designs and materials have significantly expanded …

Nationwide reduction in the number of corneal transplantations for keratoconus following the implementation of cross‐linking

DA Godefrooij, R Gans, SM Imhof… - Acta …, 2016 - Wiley Online Library
Purpose Keratoconus is characterized by corneal ectasia and irregular astigmatism, which
can lead to diminished vision and corneal scarring. Approximately 10–20% of patients with …

[HTML][HTML] Screening a panel of topical ophthalmic medications against MMP-2 and MMP-9 to investigate their potential in keratoconus management

A Belal, MA Elanany, EY Santali, AA Al-Karmalawy… - Molecules, 2022 - mdpi.com
Keratoconus (KC) is a serious disease that can affect people of any race or nationality,
although the exact etiology and pathogenic mechanism are still unknown. In this study, thirty …

Genetics vs chronic corneal mechanical trauma in the etiology of keratoconus

YS Rabinowitz, V Galvis, A Tello, D Rueda… - Experimental eye …, 2021 - Elsevier
Both genetic and environmental factors have been considered to play a role in the etiology
keratoconus. Eye rubbing, and more recently eye compression due to sleeping position …