Neuroplasticity in Parkinson's disease

BO Popescu, L Batzu, PJG Ruiz, D Tulbă… - Journal of Neural …, 2024 - Springer
Parkinson's disease (PD) is the second most frequent neurodegenerative disorder, affecting
millions of people and rapidly increasing over the last decades. Even though there is no …

Distinct dopaminergic spike-timing-dependent plasticity rules are suited to different functional roles

B Sosis, JE Rubin - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Various mathematical models have been formulated to describe the changes in synaptic
strengths resulting from spike-timing-dependent plasticity (STDP). A subset of these models …

Cortico-striatal action control inherent of opponent cognitive-motivational styles

C Avila, M Sarter - bioRxiv, 2024 - biorxiv.org
Turning on cue or stopping at a red light requires the detection of such cues to select action
sequences, or suppress action, in accordance with cue-associated action rules. Cortico …

A Mathematical Analysis of Effective Learning and Decision-Making in Neuronal Circuits

B Sosis - 2024 - d-scholarship.pitt.edu
Learning and decision-making are fundamental aspects of cognition, but much remains
unknown about how they are accomplished by the brain. We investigate these topics …