[HTML][HTML] Celastrol as an emerging anticancer agent: Current status, challenges and therapeutic strategies

C Wang, S Dai, X Zhao, Y Zhang, L Gong, K Fu… - Biomedicine & …, 2023 - Elsevier
Celastrol is a pentacyclic triterpenoid extracted from the traditional Chinese medicine
Tripterygium wilfordii Hook F., which has multiple pharmacological activities. In particular …

[HTML][HTML] A comprehensive review on pharmacological, toxicity, and pharmacokinetic properties of phillygenin: Current landscape and future perspectives

C Wang, R Wu, S Zhang, L Gong, K Fu, C Yao… - Biomedicine & …, 2023 - Elsevier
Forsythiae Fructus is a traditional Chinese medicine frequently in clinics. It is extensive in the
treatment of various inflammation-related diseases and is renowned as' the holy medicine of …

[HTML][HTML] Ugonin P inhibits lung cancer motility by suppressing DPP-4 expression via promoting the synthesis of miR-130b-5p

CY Wu, SS Ghule, CC Liaw, D Achudhan… - Biomedicine & …, 2023 - Elsevier
Lung cancer is the leading cause of cancer-related death worldwide, and the survival rate of
metastatic lung cancer is exceedingly low. Helminthostatchys Zeylanica (H. Zeylanica) is a …

[HTML][HTML] Lung cancer associated with combustion particles and fine particulate matter (PM2. 5)-The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl …

JA Holme, J Vondráček, M Machala… - Biochemical …, 2023 - Elsevier
Air pollution is the leading cause of lung cancer after tobacco smoking, contributing to 20%
of all lung cancer deaths. Increased risk associated with living near trafficked roads …

Development and application of oncolytic viruses as the nemesis of tumor cells

X Zhu, C Fan, Z Xiong, M Chen, Z Li, T Tao… - Frontiers in …, 2023 - frontiersin.org
Viruses and tumors are two pathologies that negatively impact human health, but what
occurs when a virus encounters a tumor? A global consensus among cancer patients …

Comparative proteomic profiling of plasma exosomes in lung cancer cases of liver and brain metastasis

S Li, Y Qu, L Liu, X Zhang, Y He, C Wang, Y Guo… - Cell & Bioscience, 2023 - Springer
Background Metastases within liver or the brain are the most common causes of mortality
from lung cancer (LC). Predicting liver or brain metastases before having evidence from …

[HTML][HTML] The multi-molecular mechanisms of tumor-targeted drug resistance in precision medicine

X Li, M Li, M Huang, Q Lin, Q Fang, J Liu… - Biomedicine & …, 2022 - Elsevier
Clinically, cancer drug therapy is still dominated by chemotherapy drugs. Although the
emergence of targeted drugs has greatly improved the survival rate of patients with …

[HTML][HTML] Genomic instability drives tumorigenesis and metastasis and its implications for cancer therapy

S Guo, X Zhu, Z Huang, C Wei, J Yu, L Zhang… - Biomedicine & …, 2023 - Elsevier
Genetic instability can be caused by external factors and may also be associated with
intracellular damage. At the same time, there is a large body of research investigating the …

Global respiratory health priorities at the beginning of the 21st century

CM Greene, M Abdulkadir - European Respiratory Review, 2024 - Eur Respiratory Soc
Respiratory health has become a prevailing priority amid the diverse global health
challenges that the 21st century brings, due to its substantial impact on individuals and …

Extracellular RNA as a kind of communication molecule and emerging cancer biomarker

D Wu, T Tao, EA Eshraghian, P Lin, Z Li… - Frontiers in Oncology, 2022 - frontiersin.org
Extracellular RNA (exRNA) is a special form of RNA in the body. RNA carries information
about genes and metabolic regulation in the body, which can reflect the real-time status of …