Prostanoids are the cyclooxygenase metabolites of arachidonic acid and include
prostaglandin (PG) D2, PGE2, PGF2α, PGI2, and thromboxne A2. They are synthesized and …

All organisms, from simple invertebrates to complex human beings, exist in different colors
and patterns, which arise from the unique distribution of pigments throughout the body …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

The primary function of the corpus luteum is secretion of the hormone progesterone, which is
required for maintenance of normal pregnancy in mammals. The corpus luteum develops …

It is now more than 15 years since the molecular structures of the major prostanoid receptors
were elucidated. Since then, substantial progress has been achieved with respect to …

Prostaglandins are lipid-derived autacoids that modulate many physiological systems
including the CNS, cardiovascular, gastrointestinal, genitourinary, endocrine, respiratory …

Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE2, PGF2α, PGI2,
TxA2, and PGD2. These autacrine lipid mediators interact with specific members of a family …

Eicosanoids have been implicated in a vast number of devastating inflammatory conditions,
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …

Stable cell lines that individually express the eight known human prostanoid receptors (EP1,
EP2, EP3, EP4, DP, FP, IP and TP) have been established using human embryonic kidney …

Using a compound microscope and the blood of several animals (including the elephant!),
the English anatomist, TW Jones, discovered, in 1846, that some white blood cells contained …