Dendritic spines shape analysis—classification or clusterization? Perspective

E Pchitskaya, I Bezprozvanny - Frontiers in synaptic neuroscience, 2020 - frontiersin.org
Dendritic spines are small protrusions from the dendrite membrane, where contact with
neighboring axons is formed in order to receive synaptic input. Changes in size, shape, and …

Methods of dendritic spine detection: from Golgi to high-resolution optical imaging

JJ Mancuso, Y Chen, X Li, Z Xue, STC Wong - Neuroscience, 2013 - Elsevier
Dendritic spines, the bulbous protrusions that form the postsynaptic half of excitatory
synapses, are one of the most prominent features of neurons and have been imaged and …

Recent advances in computational methods for measurement of dendritic spines imaged by light microscopy

S Okabe - Microscopy, 2020 - academic.oup.com
Dendritic spines are small protrusions that receive most of the excitatory inputs to the
pyramidal neurons in the neocortex and the hippocampus. Excitatory neural circuits in the …

Quantitative 3-D morphometric analysis of individual dendritic spines

S Basu, PK Saha, M Roszkowska, M Magnowska… - Scientific reports, 2018 - nature.com
The observation and analysis of dendritic spines morphological changes poses a major
challenge in neuroscience studies. The alterations of their density and/or morphology are …

Postpartum corticosterone administration reduces dendritic complexity and increases the density of mushroom spines of hippocampal CA 3 arbours in dams

JL Workman, S Brummelte… - Journal of …, 2013 - Wiley Online Library
Postpartum depression (PPD) affects approximately 15% of mothers after giving birth. A
complete understanding of depression during the postpartum period has yet to be …

Long-term transverse imaging of the hippocampus with glass microperiscopes

WT Redman, NS Wolcott, L Montelisciani, G Luna… - Elife, 2022 - elifesciences.org
The hippocampus consists of a stereotyped neuronal circuit repeated along the septal-
temporal axis. This transverse circuit contains distinct subfields with stereotyped connectivity …

Dendritic spine classification using shape and appearance features based on two-photon microscopy

MU Ghani, F Mesadi, SD Kanık, AÖ Argunşah… - Journal of neuroscience …, 2017 - Elsevier
Background Neuronal morphology and function are highly coupled. In particular, dendritic
spine morphology is strongly governed by the incoming neuronal activity. The first step …

DXplorer: a unified visualization framework for interactive dendritic spine analysis using 3D morphological features

JY Choi, SE Lee, YI Lee, E Cho… - … on Visualization and …, 2021 - ieeexplore.ieee.org
Dendritic spines are dynamic, submicron-scale protrusions on neuronal dendrites that
receive neuronal inputs. Morphological changes in the dendritic spine often reflect …

2dSpAn: semiautomated 2-d segmentation, classification and analysis of hippocampal dendritic spine plasticity

S Basu, D Plewczynski, S Saha, M Roszkowska… - …, 2016 - academic.oup.com
Motivation: Accurate and effective dendritic spine segmentation from the dendrites remains
as a challenge for current neuroimaging research community. In this article, we present a …

Impaired synaptic function and hyperexcitability of the pyramidal neurons in the prefrontal cortex of autism-associated Shank3 mutant dogs

F Zhu, Q Shi, Y Jiang, YQ Zhang, H Zhao - Molecular Autism, 2024 - Springer
Background SHANK3 gene is a highly replicated causative gene for autism spectrum
disorder and has been well characterized in multiple Shank3 mutant rodent models. When …