Overcoming the limited bioavailability and extensive metabolism of effective in vitro drugs
remains a challenge that limits the translation of promising drugs into clinical trials …

The increase in antimicrobial resistance (AMR) in microorganisms is a significant global
health concern. Various factors contribute to AMR, including alterations in cell membrane …

Vibrios are associated with live seafood because they are part of the indigenous marine
microflora. In Asia, foodborne infections caused by Vibrio spp. are common. In recent years …

Abstract Enterohemorrhagic Escherichia coli O157: H7 (EHEC) is responsible for outbreaks
of hemorrhagic colitis worldwide, but no effective therapy exists for EHEC infections. EHEC …

Food-related illnesses have become a growing public concern due to their considerable
socioeconomic and medical impacts. Vibrio parahaemolyticus and Staphylococcus aureus …

Staphylococcus aureus poses a significant threat in both community and hospital settings
due to its infective and pathogenic nature combined with its ability to resist the action of …

Antibiotic-resistant bacteria associated with LRTIs are frequently associated with inefficient
treatment outcomes. Antibiotic-resistant Streptococcus pneumoniae, Haemophilus …

Among the most health-influencing threats, microbial infections and cancer have attracted a
mounting interest in the medical field. To face these threats, research is directed to improve …

In this study, new derivatives based on pyridine, pyrazole, pyran, and pyranopyrimidine
scaffolds 5–14 were designed and synthesized. The newly synthesized compounds were …

: We have synthesized twenty‐three 1, 4‐dihydropyridine derivatives (1, 4‐DHPs) by using a
microwave‐assisted one‐pot multicomponent Hantzsch reaction and evaluated their …