The development of biomaterials for cardiac tissue engineering (CTE) is challenging,
primarily owing to the requirement of achieving a surface with favourable characteristics that …

Arginine-Glycine-Aspartic (RGD), is the specific recognition site of integrins with theirs
ligands, and regulates cell-cell and cell-extracellular matrix interactions. The RGD motif can …

Most current drug screening assays used to identify new drug candidates are 2D cell-based
systems, even though such in vitro assays do not adequately re-create the in vivo complexity …

The vast potential of human induced pluripotent stem-cell-derived cardiomyocytes (hiPSC-
CMs) in preclinical models of cardiac pathologies, precision medicine, and drug screening …

In the current scenario, the utility of peptide as the targeting ligand has been increased for
the efficient diagnosis and treatment of tumor cells. Blood vessels of tumor cells show some …

ABSTRACT Preclinical Research Bone is a rigid and dynamic organ that undergoes
continuous turnover. Bone homeostasis is maintained by osteoclast‐mediated bone …

Cardiovascular diseases causing high morbidity and mortality represent a major
socioeconomic burden. The primary cause of impaired heart function is often the loss of …

The present article investigates the use of a novel electrospun fibrous blend of poly (glycerol
sebacate)(PGS) and poly (butylene succinate-butylene dilinoleate)(PBS-DLA) as a …

The murine developing epicardium heterogeneously expresses the transcription factors
TCF21 and WT1. Here, we show that this cell heterogeneity is conserved in human …

Cardiac tissue engineering is a promising approach to treat cardiovascular diseases, which
are a major socio-economic burden worldwide. An optimal material for cardiac tissue …