Switchable fluorophores for single-molecule localization microscopy

H Li, JC Vaughan - Chemical reviews, 2018 - ACS Publications
The past decade has witnessed an explosion in the use of super-resolution fluorescence
microscopy methods in biology and other fields. Single-molecule localization microscopy …

Chemistry of photosensitive fluorophores for single-molecule localization microscopy

FM Jradi, LD Lavis - ACS Chemical Biology, 2019 - ACS Publications
Development of single-molecule localization microscopy (SMLM) has sparked a revolution
in biological imaging, allowing “super-resolution” fluorescence microscopy below the …

Bright photoactivatable fluorophores for single-molecule imaging

JB Grimm, BP English, H Choi, AK Muthusamy… - Nature …, 2016 - nature.com
Small-molecule fluorophores are important tools for advanced imaging experiments. We
previously reported a general method to improve small, cell-permeable fluorophores which …

A Fluorogenic ONOO-Triggered Carbon Monoxide Donor for Mitigating Brain Ischemic Damage

L Xing, B Wang, J Li, X Guo, X Lu, X Chen… - Journal of the …, 2022 - ACS Publications
Ischemia–reperfusion (I/R) injuries are from the secondary radicals of ONOO–. Direct radical
scavenging is difficult because of their high reactivity. ONOO–is longer-lived than the …

General synthetic method for Si-fluoresceins and Si-rhodamines

JB Grimm, TA Brown, AN Tkachuk… - ACS Central Science, 2017 - ACS Publications
The century-old fluoresceins and rhodamines persist as flexible scaffolds for fluorescent and
fluorogenic compounds. Extensive exploration of these xanthene dyes has yielded general …

Photoactivatable fluorescent dyes with hydrophilic caging groups and their use in multicolor nanoscopy

AN Butkevich, M Weber… - Journal of the …, 2021 - ACS Publications
We propose a series of fluorescent dyes with hydrophilic carbamate caging groups that
undergo rapid photoactivation under UV (≤ 400 nm) irradiation but do not undergo spurious …

Triarylmethane fluorophores resistant to oxidative photobluing

AN Butkevich, ML Bossi, G Lukinavičius… - Journal of the …, 2018 - ACS Publications
Spectral stability of small-molecule fluorescent probes is required for correct interpretation
and reproducibility of multicolor fluorescence imaging data, in particular under high (de) …

[PDF][PDF] Super-resolved fluorescence microscopy: Nobel Prize in Chemistry 2014 for Eric Betzig, Stefan Hell, and William E. Moerner.

L Möckl, DC Lamb, C Bräuchle - Angewandte Chemie International …, 2014 - academia.edu
Δxmin, Δymin ¼ λ/2n sin α ð Þ λ/2 where λ is the wavelength of the light, n the index of
refraction of the microscopy medium and α half the aperture angle of the objective lens.[1] …

Synthesis of a far‐red photoactivatable silicon‐containing rhodamine for super‐resolution microscopy

JB Grimm, T Klein, BG Kopek… - Angewandte Chemie …, 2016 - Wiley Online Library
The rhodamine system is a flexible framework for building small‐molecule fluorescent
probes. Changing N‐substitution patterns and replacing the xanthene oxygen with a …

A Photoactivatable BODIPY Probe for Localization‐Based Super‐Resolution Cellular Imaging

CS Wijesooriya, JA Peterson, P Shrestha… - Angewandte …, 2018 - Wiley Online Library
The synthesis and application of a photoactivatable boron‐alkylated BODIPY probe for
localization‐based super‐resolution microscopy is reported. Photoactivation and excitation …