The presence of a mucus layer that covers the surface of a variety of organs has been
capitalized to develop mucoadhesive dosage forms that remain in the administration site for …

The process of mucoadhesion involving a polymeric drug delivery platform is a complex one
that includes wetting, adsorption and interpenetration of polymer chains amongst various …

This review focuses on two formulation approaches, mucoadhesion and thermogelling,
intended for prolonging residence time on vaginal mucosa of medical devices or drug …

The vagina is an important area of the reproductive tract and serves as a potential route of
drug administration. Beside locally acting drugs it is also of importance for systemic drug …

This thoroughly revised and expanded reference provides authoritative discussions on the
physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors …

Vaginal drug delivery systems are often preferred for treating a variety of diseases and
conditions of the female reproductive tract (FRT), as delivery can be more targeted with less …

Introduction: The benefits of mucoadhesive systems are related to the increased in situ
residence and intimate contact of the delivery vehicle with the mucosa. The recent …

A key property of mucin glycoproteins is their exceptional capacity to hydrate and lubricate
surfaces. In vivo, mucins assemble into mucus hydrogels that cover the epithelium and …

Pegylated nanoparticles based on poly (methyl vinyl ether-co-maleic anhydride)(PVM/MA)
were prepared by simple solvent displacement method, in the absence of catalysts or …

The rate of molecular transport through the mucus gel can be an important determinant of
efficacy for therapeutic agents delivered by oral, intranasal, intravaginal/rectal, and …