The microbiota-derived metabolite indole decreases mucosal inflammation and injury in a murine model of NSAID enteropathy

CM Whitfield-Cargile, ND Cohen, RS Chapkin… - Gut …, 2016 - Taylor & Francis
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently used classes
of medications in the world. Unfortunately, NSAIDs induce an enteropathy associated with …

Regulation of T cell expansion by antigen presentation dynamics

A Mayer, Y Zhang, AS Perelson… - Proceedings of the …, 2019 - National Acad Sciences
An essential feature of the adaptive immune system is the proliferation of antigen-specific
lymphocytes during an immune reaction to form a large pool of effector cells. This …

CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver

CY Yang, JB Chen, TF Tsai, YC Tsai, CY Tsai… - PloS one, 2013 - journals.plos.org
CLEC4F, a member of C-type lectin, was first purified from rat liver extract with high binding
affinity to fucose, galactose (Gal), N-acetylgalactosamine (GalNAc), and un-sialylated …

Zinc dyshomeostasis during polymicrobial sepsis in mice involves zinc transporter Zip14 and can be overcome by zinc supplementation

I Wessels, RJ Cousins - American Journal of Physiology …, 2015 - journals.physiology.org
Integrity of the immune system is particularly dependent on the availability of zinc. Recent
data suggest that zinc is involved in the development of sepsis, a life-threatening systemic …

CD40L Expression Allows CD8+ T Cells to Promote Their Own Expansion and Differentiation through Dendritic Cells

NQ Tay, DCP Lee, YL Chua, N Prabhu… - Frontiers in …, 2017 - frontiersin.org
CD8+ T cells play an important role in providing protective immunity against a wide range of
pathogens, and a number of different factors control their activation. Although CD40L …

Vaccine-induced inflammation and inflammatory monocytes promote CD4+ T cell-dependent immunity against murine salmonellosis

N Wang, TA Scott, A Kupz, MM Shreenivas… - PLoS …, 2023 - journals.plos.org
Prior infection can generate protective immunity against subsequent infection, although the
efficacy of such immunity can vary considerably. Live-attenuated vaccines (LAVs) are one of …

Profiling of Indigenous Biosurfactant‐Producing Bacillus Isolates in the Bioremediation of Soil Contaminated by Petroleum Products and Olive Oil

PS Elenga-Wilson, CA Kayath… - International Journal …, 2021 - Wiley Online Library
Petroleum is, up to this date, an inimitable nonrenewable energy resource. Petroleum
leakage, which arises during transport, storage, and refining, is the most important …

Use of a genetically engineered E. coli overexpressing β-glucuronidase accompanied by glycyrrhizic acid, a natural and anti-inflammatory agent, for directed …

A Afkhami-Poostchi, M Mashreghi, M Iranshahi… - International Journal of …, 2020 - Elsevier
Bacteria-directed enzyme prodrug therapy (BDEPT), is an emerging alternative directed and
tumor-specific approach. The basis of this method is the conversion of a non-toxic prodrug …

Determination of virulence and antibiotic resistance pattern of biofilm producing Listeria species isolated from retail raw milk

KM Osman, A Samir, UH Abo-Shama, EH Mohamed… - BMC microbiology, 2016 - Springer
Background One of the foodborne pathogens is Listeria monocytogenes, which causes
serious invasive illness in elderly and immunocompromised patients, pregnant women …

The TRPM2 Ion Channel Regulates Inflammatory Functions of Neutrophils During Listeria monocytogenes Infection

FH Robledo-Avila, JD Ruiz-Rosado… - Frontiers in …, 2020 - frontiersin.org
During infection, phagocytic cells pursue homeostasis in the host via multiple mechanisms
that control microbial invasion. Neutrophils respond to infection by exerting a variety of …