Biofilm matrixome: extracellular components in structured microbial communities

L Karygianni, Z Ren, H Koo, T Thurnheer - Trends in microbiology, 2020 - cell.com
Biofilms consist of microbial communities embedded in a 3D extracellular matrix. The matrix
is composed of a complex array of extracellular polymeric substances (EPS) that contribute …

Surviving as a community: antibiotic tolerance and persistence in bacterial biofilms

J Yan, BL Bassler - Cell host & microbe, 2019 - cell.com
Biofilms are surface-associated bacterial communities that play both beneficial and harmful
roles in nature, medicine, and industry. Tolerant and persister cells are thought to underlie …

Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Proliferating active matter

O Hallatschek, SS Datta, K Drescher, J Dunkel… - Nature Reviews …, 2023 - nature.com
The fascinating patterns of collective motion created by autonomously driven particles have
fuelled active-matter research for over two decades. So far, theoretical active-matter …

[HTML][HTML] Physico-chemistry from initial bacterial adhesion to surface-programmed biofilm growth

V Carniello, BW Peterson, HC van der Mei… - Advances in colloid and …, 2018 - Elsevier
Biofilm formation is initiated by adhesion of individual bacteria to a surface. However,
surface adhesion alone is not sufficient to form the complex community architecture of a …

Spatial structure, cooperation and competition in biofilms

CD Nadell, K Drescher, KR Foster - Nature Reviews Microbiology, 2016 - nature.com
Bacteria often live within matrix-embedded communities, termed biofilms, which are now
understood to be a major mode of microbial life. The study of biofilms has revealed their vast …

Emergence of three-dimensional order and structure in growing biofilms

R Hartmann, PK Singh, P Pearce, R Mok, B Song… - Nature physics, 2019 - nature.com
Surface-attached bacterial biofilms are self-replicating active liquid crystals and the
dominant form of bacterial life on Earth,,–. In conventional liquid crystals and solid-state …

Mechanisms Underlying Vibrio cholerae Biofilm Formation and Dispersion

JK Teschler, CD Nadell, K Drescher… - Annual Review of …, 2022 - annualreviews.org
Biofilms are a widely observed growth mode in which microbial communities are spatially
structured and embedded in a polymeric extracellular matrix. Here, we focus on the model …

Bacteria solve the problem of crowding by moving slowly

OJ Meacock, A Doostmohammadi, KR Foster… - Nature Physics, 2021 - nature.com
Bacteria commonly live attached to surfaces in dense collectives containing billions of cells.
While it is known that motility allows these groups to expand en masse into new territory …

Dynamic biofilm architecture confers individual and collective mechanisms of viral protection

L Vidakovic, PK Singh, R Hartmann, CD Nadell… - Nature …, 2018 - nature.com
In nature, bacteria primarily live in surface-attached, multicellular communities, termed
biofilms,,,,–. In medical settings, biofilms cause devastating damage during chronic and …