The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

One of the major impediments to drug development is low aqueous solubility and thus poor
bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the …

Ocular drug delivery is a significantly challenging task due to the presence of various
anatomical and physiological barriers in the eye. Naturally available polysaccharides, when …

Background Hyaluronic acid (HA) is a natural polysaccharide that is available as a food
additive and dietary supplement. As HA can specifically bind multiple receptors (eg, cluster …

Eyes are directly exposed to the outer environment and susceptible to infections, leading to
various ocular disorders. Local medication is preferred to treat eye diseases due to its …

Ocular disorders comprising various diseases of the anterior and posterior segments are
considered as the main reasons for blindness. Natural products have been identified as …

Posterior segment diseases, such as age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are vital factor that seriously threatens human vision health and quality of …

Liposomes are promising spherical vesicles for topical drug delivery to the eye. Several
types of vesicles were formulated in this study, including conventional, PEGylated, and …

The eye is a complex part of the body that has various physiological barriers to protect it from
foreign substances. However, changes to these defense mechanisms can cause eye injury …