Organelles of the central membrane system of higher eukaryotes have been shown to utilize
microtubules both for maintenance of their characteristic spatial distributions and for efficient …

抄録 In this paper, we review the structure and function of a unique type of actin-related
intercellular adhesion junctions in the testis. Based on their ultrastructure, the junctions are …

WE have hypothesized that end-to-end chromosome fusions observed in some tumours
could play a part in genetic instability associated with tumorigenesis and that fusion may …

Axonal transport has been intensively examined as a good model for studying the
mechanism of organelle transport in cells, but it is still unclear how different types of …

Proteolytic processing of amyloid precursor protein (APP) generates amyloid-β peptide and
has been implicated in the pathogenesis of Alzheimer's disease. However, the normal …

Kinesin superfamily proteins (KIFs) are the molecular motors conveying cargos along
microtubules. KIF5s, the heavy chains of conventional kinesin (KHC), are originally identified …

In A. nidulans, the temperature-sensitive cell cycle mutation bimC4 causes an elevated
mitotic index at restrictive temperature. Under restrictive conditions the mutation interferes …

When not bound to cargo, the motor protein kinesin is in an inhibited state that has low
microtubule-stimulated ATPase activity. Inhibition serves to minimize the dissipation of ATP …

Chicken myosin-V is a member of a recently recognized class of myosins distinct from both
the myosins-I and the myosins-II. We report here the purification, electron microscopic …

Conventional kinesin transports membranes along microtubules in vivo, but the majority of
cellular kinesin is unattached to cargo. The motility of non-cargo-bound, soluble kinesin may …