SPH Alexander, HE Benson… - British journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
B Roy, A Depaix, C Périgaud, S Peyrottes - Chemical Reviews, 2016 - ACS Publications
Focusing on the recent literature (since 2000), this review outlines the main synthetic approaches for the preparation of 5′-mono-, 5′-di-, and 5′-triphosphorylated …
I von Kuegelgen - Biochemical Pharmacology, 2021 - Elsevier
Abstract Professor Geoffrey Burnstock proposed the concept of purinergic signaling via P1 and P2 receptors. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular …
I von Kügelgen - Brain research bulletin, 2019 - Elsevier
Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …
The medicinal chemistry and pharmacology of the four subtypes of adenosine receptors (ARs) and the eight subtypes of P2Y receptors (P2YRs, activated by a range of purine and …
Abstract P2Y receptors (P2YRs) are a family of G protein-coupled receptors activated by extracellular nucleotides. Physiological P2YR agonists include purine and pyrimidine …
Abstract Adenosine 5′-triphosphate (ATP) is found in high concentrations in the extracellular microenvironment of tumours and is postulated to play critical roles in cancer …