Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory
response. They become reactive in response to virtually all pathological situations in the …

Glioblastoma (GBM) is an aggressive primary tumor, causing thousands of deaths
worldwide every year. The mean survival of patients with GBM remains below 20 months …

Astrocytes exist throughout the nervous system and are proposed to affect neural circuits
and behavior. However, studying astrocytes has proven difficult because of the lack of tools …

We provide an overview of recent progress on the study of astrocyte intracellular Ca2+
signaling. We consider the methods that have been used to monitor astrocyte Ca2+ signals …

Astrocytes have emerged as important partners of neurons in information processing.
Important progress has been made in the past two decades in understanding the role of …

Astrocytes are involved in the neuroinflammation of neurodegenerative diseases, such as
Parkinson's disease (PD). Among the numerous inflammatory cytokines, interleukin-1β (IL …

Astrocytes, which are homeostatic cells of the central nervous system (CNS), display
remarkable heterogeneity in their morphology and function. Besides their physical and …

Gene therapy holds promise for the treatment of many pathologies of the central nervous
system (CNS), including brain tumors and neurodegenerative diseases. However, the …

Astrocytes are dynamic cells that maintain brain homeostasis, regulate neurotransmitter
systems, and process synaptic information, energy metabolism, antioxidant defenses, and …

Many brain functions depend on the ability of neural networks to temporally integrate
transient inputs to produce sustained discharges. This can occur through cell-autonomous …