Inflammation is a body response against infection that activates other biological components
that include various cytokines, chemokines and other biological compounds that trigger …

Malononitrile dimer as a precursor reactant has been extensively applied in the diversity-
oriented synthesis of various heterocyclic motifs, bis-heterocyclic compounds, fused …

The synthesis of a number of benzimidazole Schiff bases 3 and 3-oxo-pyrimido [1, 2-a]
benzimidazoles 4 in excellent yields by a one-step sequence from the reaction of 2 …

A series of adamantane derivatives of thiazolyl-N-substituted amides were synthesized in a
three-step reaction and tested for anti-inflammatory activity as well as lipoxygenase and …

Abstract Some derivatives containing pyrido [2, 3-d: 6, 5d′] dipyrimidine-4, 5-diones (9a-f),
tetrahydropyrido [2, 3-d] pyrimidine-6-carbonitriles (11a-c) and 6-(4-acetylphenyl)-2-thioxo …

Kröhnke pyridines: an efficient solvent-free synthesis of 2,4,6-triarylpyridines - ScienceDirect
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This study presents a new environmentally sustainable catalytic method for the synthesis of
symmetrically substituted pyridine derivatives and substituted alkene derivatives using zinc …

A series of N-substituted-quinolinone-3-aminoamides and their hybrids containing the α-
lipoic acid functionality were designed and synthesized as potential bifunctional agents …

Nuclear factor-kappaB (NF-κB) has been reported to regulate various genes involved in
cancer and inflammation. Accordingly, drugs suppressing or inhibiting NF-κB may possess …

Substituted thiazoles with different structural features were synthesized and screened for
their anti-inflammatory activity in acute carrageenin induced rat paw edema model and …