Glucose-6-phosphate dehydrogenase: update and analysis of new mutations around the world

S Gómez-Manzo, J Marcial-Quino… - International journal of …, 2016 - mdpi.com
Glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme in the pentose
phosphate pathway which produces nicotinamide adenine dinucleotide phosphate …

Glucose-6-phosphate dehydrogenase deficiency

L Luzzatto, M Ally, R Notaro - … Journal of the American Society of …, 2020 - ashpublications.org
Abstract Glucose 6-phosphate dehydrogenase (G6PD) deficiency is 1 of the commonest
human enzymopathies, caused by inherited mutations of the X-linked gene G6PD. G6PD …

Human salivary proteome—a resource of potential biomarkers for oral cancer

P Sivadasan, MK Gupta, GJ Sathe, L Balakrishnan… - Journal of …, 2015 - Elsevier
Proteins present in human saliva offer an immense potential for clinical applications.
However, exploring salivary proteome is technically challenged due to the presence of …

Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency

N Horikoshi, S Hwang, C Gati… - Proceedings of the …, 2021 - National Acad Sciences
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common blood
disorder, presenting multiple symptoms, including hemolytic anemia. It affects 400 million …

The stability of G6PD is affected by mutations with different clinical phenotypes

S Gómez-Manzo, J Terrón-Hernández… - International journal of …, 2014 - mdpi.com
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme
deficiency worldwide, causing a wide spectrum of conditions with severity classified from the …

An overall view of the functional and structural characterization of glucose-6-phosphate dehydrogenase variants in the Mexican population

B Hernández-Ochoa, D Ortega-Cuellar… - International Journal of …, 2023 - mdpi.com
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, affecting an estimated 500 million
people worldwide, is a genetic disorder that causes human enzymopathies. Biochemical …

G6PDH as a key immunometabolic and redox trigger in arthropods

B Moraes, R Martins, C Lopes, R Martins… - Frontiers in …, 2023 - frontiersin.org
The enzyme glucose-6-phosphate dehydrogenase (G6PDH) plays crucial roles in glucose
homeostasis and the pentose phosphate pathway (PPP), being also involved in redox …

Coupling between protein stability and catalytic activity determines pathogenicity of G6PD variants

AD Cunningham, A Colavin, KC Huang… - Cell reports, 2017 - cell.com
G6PD deficiency, an enzymopathy affecting 7% of the world population, is caused by over
160 identified amino acid variants in glucose-6-phosphate dehydrogenase (G6PD). The …

[HTML][HTML] A trade off between catalytic activity and protein stability determines the clinical manifestations of glucose-6-phosphate dehydrogenase (G6PD) deficiency

U Boonyuen, K Chamchoy, T Swangsri… - International journal of …, 2017 - Elsevier
Abstract Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common
polymorphism and enzymopathy in humans, affecting approximately 400 million people …

Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia

E Lo, D Zhong, B Raya, K Pestana, C Koepfli, MC Lee… - Malaria journal, 2019 - Springer
Background G6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency
of the G6PD enzyme can cause free radical-mediated oxidative damage to red blood cells …