Mechanisms of nonsteroidal anti-inflammatory drugs in cancer prevention

A Umar, VE Steele, DG Menter, ET Hawk - Seminars in oncology, 2016 - Elsevier
Various clinical and epidemiologic studies show that nonsteroidal anti-inflammatory drugs
(NSAIDs), including aspirin and cyclooxygenase inhibitors (COXIBs) help prevent cancer …

The intestinal absorption of triptolide for the treatment of rheumatoid arthritis is mediated by transporters

Z Guo, H Wang, J Sun, Y Ma, X Cui, S Kou… - International …, 2024 - Elsevier
Tripterygium wilfordii Hook. f. is a traditional Chinese herb that is used to treat rheumatoid
arthritis (RA). Triptolide (TP), an epoxidized diterpene lactone extracted from this herb, has …

Prediction the substrate specificities of membrane transport proteins based on support vector machine and hybrid features

L Li, J Li, W Xiao, Y Li, Y Qin, S Zhou… - IEEE/ACM Transactions …, 2015 - ieeexplore.ieee.org
Membrane transport proteins and their substrate specificities play crucial roles in a variety of
cellular functions. Identifying the substrate specificities of membrane transport proteins is …

Prostaglandin transporting protein-mediated prostaglandin E2 transport in lipopolysaccharide-inflamed rat dental pulp

N Ohkura, Y Shigetani, N Yoshiba, K Yoshiba… - Journal of endodontics, 2014 - Elsevier
Abstract Introduction The prostaglandin transporter (Pgt) and multidrug resistance-
associated protein (Mrp) 4 are membrane transport proteins that play crucial roles in the …

Pulmonary inflammation caused by cigarette smoke combined with lipopolysaccharide up-regulated OATP2B1 in rat lung tissue and pulmonary epithelial cells

Z Wang, X Fang, S Zhang, J Song - Experimental Lung Research, 2022 - Taylor & Francis
Organic anion transport polypeptide 2B1 (OATP2B1), as an uptake transporter, is involved in
the transport of many related substrate drugs and endogenous substances in the lungs. A …

[引用][C] Selective and cytokine-dependent regulation of hepatic transporters and bile acid homeostasis during infectious colitis in mice

MD Merrell, BA Nyagode, JD Clarke… - Drug Metabolism and …, 2014 - ASPET

[引用][C] 内毒素脂多糖对药物转运体的影响研究进展

刘霏 - 解放军药学学报, 2015

歯髄創傷治癒のメカニズム―プロスタグランジンE2を中心に―

大倉直人, 野杁由一郎 - 日本歯内療法学会雑誌, 2018 - jstage.jst.go.jp
以上の報告から, PGE2 が全身や歯髄組織においてさまざまな生理学的機能や効果を有している
ことに論をまたない. そこで,「PGE2 はどのように必要とされる部位に運ばれているのだろう」 …