Maternal immune activation by poly I: C as a preclinical model for neurodevelopmental disorders: a focus on autism and schizophrenia

FL Haddad, SV Patel, S Schmid - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

[HTML][HTML] Microglia and BDNF at the crossroads of stressor related disorders: Towards a unique trophic phenotype

N Prowse, S Hayley - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Stressors ranging from psychogenic/social to neurogenic/injury to systemic/microbial can
impact microglial inflammatory processes, but less is known regarding their effects on …

Structural and functional deviations of the hippocampus in schizophrenia and schizophrenia animal models

D Wegrzyn, G Juckel, A Faissner - International Journal of Molecular …, 2022 - mdpi.com
Schizophrenia is a grave neuropsychiatric disease which frequently onsets between the end
of adolescence and the beginning of adulthood. It is characterized by a variety of …

The sex-dependent response to psychosocial stress and ischaemic heart disease

TJ Helman, JP Headrick, NJC Stapelberg… - Frontiers in …, 2023 - frontiersin.org
Stress is an important risk factor for modern chronic diseases, with distinct influences in
males and females. The sex specificity of the mammalian stress response contributes to the …

[HTML][HTML] Epigenetic Modifications and Neuroplasticity in the Pathogenesis of Depression: A Focus on Early Life Stress

BM Benatti, A Adiletta, P Sgadò, A Malgaroli… - Behavioral …, 2024 - mdpi.com
Major depressive disorder (MDD) is a debilitating mental illness, and it is considered to be
one of the leading causes of disability globally. The etiology of MDD is multifactorial …

The thalamic midline nucleus reuniens: potential relevance for schizophrenia and epilepsy

MJ Dolleman-van Der Weel, MP Witter - Neuroscience & Biobehavioral …, 2020 - Elsevier
Anatomical, electrophysiological and behavioral studies in rodents have shown that the
thalamic midline nucleus reuniens (RE) is a crucial link in the communication between …

Delayed effects of neonatal immune activation on brain neurochemistry and hypothalamic–pituitary–adrenal axis functioning

JN Khantakova, NP Bondar… - European Journal of …, 2022 - Wiley Online Library
During the postnatal period, the brain is highly sensitive to stress and inflammation, which
are hazardous to normal growth and development. There is increasing evidence that …

miR-142-3p regulates BDNF expression in activated rodent microglia through its target CAMK2A

N Gupta, S Jadhav, KL Tan, G Saw… - Frontiers in cellular …, 2020 - frontiersin.org
Microglia, the innate immune effector cells of the mammalian central nervous system (CNS),
are involved in the development, homeostasis, and pathology of CNS. Microglia become …

Putative role of mitochondria in SARS-CoV-2 mediated brain dysfunctions: A prospect

SK Maurya, MS Baghel, Gaurav… - Biotechnology and …, 2023 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic. Though the virus primarily damages the respiratory and cardiovascular …

Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3/NF-κB pathway and anxiety-like behavior in male C57BL/6 mice

X Wang, H Yu, C Wang, Y Liu, J You, P Wang, G Xu… - Toxicology, 2020 - Elsevier
Chronic alcoholism has become a major public health problem. Long-term and excessive
drinking can lead to a variety of diseases. Chronic ethanol exposure can induce …