Abstract N 6-methyladenosine (m 6 A) is the most prevalent internal mRNA modification.
Recent research has highlighted its role as a key regulator of gene expression, influencing …

Abstract N 6-methyladenosine (m6A) represents the most prevalent internal and reversible
modification on RNAs. Different cell types display their unique m6A profiles, which are …

Ythdf2 is known to mediate mRNA degradation in an m 6 A-dependent manner, and it has
been shown to play a role in skeletal muscle differentiation. Recently, Ythdf2 was also found …

Highlights•Epitranscriptomics refers to all chemical marks on RNA regulating gene
expression.•The epitranscriptome is altered in several prevalent diseases.•Disease-specific …

Long-term durable remission in patients with B cell malignancies following chimeric antigen
receptor (CAR)-T cell immunotherapy remains unsatisfactory, often due to antigen escape …

Abstract N 6-methyladenosine (m 6 A) is one of the most common modifications of RNA in
eukaryotic cells and is involved in mRNA metabolism, including stability, translation …

Abstract microRNAs (miRNAs) are short single-stranded non-coding RNAs between 21 and
25 nt in length in eukaryotic organisms, which control post-transcriptional gene expression …

The post-transcriptional regulation of epigenetic modification is a hot topic in skeletal muscle
development research. Both m6A modifications and miRNAs have been well-established as …

Dysregulated RNA modifications, stemming from the aberrant expression and/or malfunction
of RNA modification regulators operating through various pathways, play pivotal roles in …

Skeletal system disease (SSD) is defined as a class of chronic disorders of skeletal system
with poor prognosis and causes heavy economic burden. m6A, methylation at the N6 …