Zoonotic Hantaviridae with Global Public Health Significance

RX Chen, HY Gong, X Wang, MH Sun, YF Ji, SM Tan… - Viruses, 2023 - mdpi.com
Hantaviridae currently encompasses seven genera and 53 species. Multiple hantaviruses
such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus …

Favipiravir in the battle with respiratory viruses

JM Smyk, A Majewska - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Among antiviral drugs, the vast majority targets only one or two related viruses. The
conventional model, one virus-one drug, significantly limits therapeutic options. Therefore, in …

In Vitro Anti-Orthohantavirus Activity of the High-and Low-Molecular-Weight Fractions of Fucoidan from the Brown Alga Fucus evanescens

NV Krylova, AS Silchenko, AB Pott, SP Ermakova… - Marine Drugs, 2021 - mdpi.com
The Hantaan orthohantavirus (genovariant Amur–AMRV) is a rodent-borne zoonotic virus; it
is the causative agent of haemorrhagic fever with renal syndrome in humans. The currently …

Nlrc3 Knockout Mice Showed Renal Pathological Changes After HTNV Infection

R Ma, X Zhang, J Shu, Z Liu, W Sun, S Hou… - Frontiers in …, 2021 - frontiersin.org
Hantaan virus (HTNV) infects humans and causes hemorrhagic fever with renal syndrome
(HFRS). The development of well-characterized animal models of HFRS could accelerate …

[HTML][HTML] A fatal case of haemorrhagic fever with renal syndrome in Kursk Region, Russia, caused by a novel Puumala virus clade

E Blinova, A Deviatkin, S Kurashova… - Infection, Genetics and …, 2022 - Elsevier
Haemorrhagic fever with renal syndrome (HFRS) is the most widespread natural-focal
human disease in the Russian Federation. In this study, we report virological assessment of …

[HTML][HTML] Evolutionary formation and distribution of Puumala virus genome variants, Russia

E Blinova, A Deviatkin, M Makenov… - Emerging infectious …, 2023 - ncbi.nlm.nih.gov
We analyzed Puumala virus (PUUV) sequences collected from bank voles from different
regions of Russia. Phylogenetic analysis revealed PUUV reassortments in areas with the …

Diverse susceptibilities and responses of human and rodent cells to orthohantavirus infection reveal different levels of cellular restriction

G Gallo, P Kotlik, P Roingeard, M Monot… - PLOS Neglected …, 2022 - journals.plos.org
Orthohantaviruses are rodent-borne emerging viruses that may cause severe diseases in
humans but no apparent pathology in their small mammal reservoirs. However, the …

Great genetic diversity of vector-borne bacteria and protozoan in wild rodents from Guangxi, China

J Xue, SS Chen, R Jian, GQ Chen, X Qin… - PLOS Neglected …, 2024 - journals.plos.org
Background Rodents are recognized as the hosts of many vector-borne bacteria and
protozoan parasites and play an important role in their transmission and maintenance …

The discovery of novel variants reveals the genetic diversity and potential origin of Seoul orthohantavirus

G Kuang, J Wang, Y Feng, W Wu, X Han… - PLOS Neglected …, 2024 - journals.plos.org
Seoul orthohantavirus (SEOV) has been identified as one of the main causative agents of
hemorrhagic fever with renal syndrome (HFRS) in China. The virus was found circulating in …

A Development of Rapid Whole-Genome Sequencing of Seoul orthohantavirus Using a Portable One-Step Amplicon-Based High Accuracy Nanopore System

K Park, J Noh, K Kim, J Kim, HK Cho, SG Kim, E Yang… - Viruses, 2023 - mdpi.com
Whole-genome sequencing provides a robust platform for investigating the epidemiology
and transmission of emerging viruses. Oxford Nanopore Technologies allows for real-time …