Current studies on molecular mechanisms of insulin resistance

J Pei, B Wang, D Wang - Journal of Diabetes Research, 2022 - Wiley Online Library
Diabetes is a metabolic disease that raises the risk of microvascular and neurological
disorders. Insensitivity to insulin is a characteristic of type II diabetes, which accounts for 85 …

Emerging perspectives on the set of conditions that Lead to the emergence of metabolic syndrome

BM Tarcău, LG Vicaș, L Filip, F Maghiar… - Journal of Personalized …, 2023 - mdpi.com
Metabolic syndrome, as a medical condition, presents multifactorial complexity that is
characterized by the resulting damage from genetic, environmental, and lifestyle factors …

Differential expression of insulin receptor substrate-1 (IRS-1) in visceral and subcutaneous adipose depots of morbidly obese subjects undergoing bariatric surgery in …

M Sharma, S Aggarwal, U Nayar, NK Vikram… - Diabetes & Metabolic …, 2021 - Elsevier
Background/aim: Abdominal obesity and associated metabolic consequences are a
burgeoning problem in Asian Indians and studying their genetic predisposition is important …

Research progress on the association of insulin resistance with type 2 diabetes mellitus and Alzheimer's disease

M Zheng, C Wang, M Hu, Q Li, J Li, S Quan… - Metabolic Brain …, 2025 - Springer
Type 2 diabetes mellitus (T2DM) is a metabolic disorder that is characterized by insulin
resistance and hyperglycemia. It is also known to be a risk factor for Alzheimer's disease …

Low and insufficient birth weights as important factors of developmental stages of type 2 diabetes: Intergenerational Limache Cohort study

IP González, S López-Arana, J Mattei - Diabetes & Metabolic Syndrome …, 2022 - Elsevier
Background & aims This study aimed to investigate the association of birth weight with
developmental stages of Type 2 Diabetes among Chilean young adults. Methods A …

The 2039 A/G FSH receptor gene polymorphism influences glucose metabolism in healthy men

R Cannarella, N Musso, RA Condorelli, M Musmeci… - Endocrine, 2020 - Springer
Objective To assess the role of c. 2039 A/G (p. Asp680Ser)(rs6166) and c.− 29 G/A
(rs1394205) follicle-stimulating hormone receptor (FSHR) gene single nucleotide …

Genetic Polymorphisms and Their Interactions with the Risk Factors of Cardiovascular Diseases: Review Chapter

JM Chalwe, C Grobler… - Risk Factors for …, 2021 - books.google.com
Cardiovascular diseases (CVDs) have been reported to have a complex pathogenesis by a
number of studies. Atherosclerosis and inflammation have been established as the main …

POLIMORFISMO GLY972ARG DEL GEN IRS1 EN PACIENTES CON OBESIDAD MORBIDA

H Rangel, G Fernández, J Pestana, GB Pérez… - Acta Científica de la …, 2023 - saber.ucv.ve
Existen numerosos genes asociados a enfermedades metabólicas, entre estos se
encuentran el gen codificante del sustrato del receptor de insulina 1 (IRS1)(rs1801278), que …

Effects of MIR-222 on metabolic programming in obesity-impact on insulin signalling pathway

P Bibiloni Coll - dspace.uib.es
[eng] Obesity is a multifactorial disease of worldwide high-prevalence. The mechanisms
behind it are still not completely elucidated. This pathology is usually correlated with insulin …