The comet assay in animal models: From bugs to whales–(Part 1 Invertebrates)

G Gajski, B Žegura, C Ladeira, B Pourrut… - … Research/Reviews in …, 2019 - Elsevier
The comet assay, also called single cell gel electrophoresis, is a sensitive, rapid and low-
cost technique for quantifying and analysing DNA damage and repair at the level of …

Nanotoxicity of silver nanoparticles on HEK293T cells: A combined study using biomechanical and biological techniques

X Jiang, C Lu, M Tang, Z Yang, W Jia, Y Ma, P Jia… - ACS …, 2018 - ACS Publications
Human embryonic kidney 293T cells (HEK293T cells) before and after treatment with silver
nanoparticles (AgNPs) were measured using advanced atomic force microscopy (AFM) …

Genotoxicity assessment of pesticide profenofos in freshwater fish Channa punctatus (Bloch) using comet assay and random amplified polymorphic DNA (RAPD)

AK Pandey, NS Nagpure, SP Trivedi - Chemosphere, 2018 - Elsevier
The present study explored the induced genotoxicity (DNA damage) due to
organophosphate pesticide profenofos (PFF) after in vivo exposure in freshwater fish …

Synthesis and radioprotective activity of mitochondria targeted dihydropyridines in vitro

Y Zhang, J Wang, Y Li, F Wang, F Yang… - International Journal of …, 2017 - mdpi.com
The radiation-induced damage to mitochondrial oxidative respiratory chain could lead to
generating of superoxide anions (O2−) and secondary reactive oxygen species (ROS) …

Protective Effects of 2-Amino-5,6-dihydro-4H-1,3-thiazine and Its Derivative against Radiation-Induced Hematopoietic and Intestinal Injury in Mice

Y Li, S Kong, F Yang, W Xu - International Journal of Molecular Sciences, 2018 - mdpi.com
Ionizing radiation (IR) acts as an external stimulating factor, when it acts on the body, it will
activate NF-κ B and cause the up-regulation of inducible nitric oxide synthase (iNOS) and …

Evaluation of gamma radiation–induced genotoxicity in the workers of Italian honey bees, Apis mellifera ligustica, using single cell gel electrophoresis (comet) assay

PM Shameer, NJ Shetty, N Narayanappa… - Journal of Apicultural …, 2024 - Taylor & Francis
The environment exposed to radionuclide faces detrimental effects of ionizing radiations and
these radiations can damage DNA by inducing genotoxicity in living organisms. The gamma …

The research of genetic toxicity of β-phellandrene

Z Cheng, J Jiang, X Yang, H Chu, M Jin, Y Li… - Environmental …, 2017 - Elsevier
Abstract β-Phellandrene, a plant extract, can be used as natural pesticides and synthetic
materials. As a factor that human may be exposed to, the toxicity information about β …

Association among blood BPDE-DNA adduct, serum interleukin-8 (IL-8) and DNA strand breaks for children with pulmonary diseases

H Kuang, Y Dai, X Ding, Y Li, C Cha… - International Journal …, 2021 - Taylor & Francis
Exposure to benzo [a] pyrene (B [a] P) may be a risk factor for pulmonary diseases. To
investigate the correlations among B [a] P exposure level, DNA strand breaks and …

分子生物学水平的生物剂量学指标研究现状

马娅, 李洁清, 侯殿俊, 朱建国 - 国际放射医学核医学杂志, 2018 - ijrmnm.com
生物剂量学指标在核事故受照人员剂量估算及辐射生物效应研究中具有重要作用,
而现有的染色体畸变分析不能满足大量快速检测的需求. 因此, 寻找快速, 简便 …

Temperature Modulated Genotoxicity in Coelomocytes of Ecologically Different Earthworm Species Exposed to Sub-lethal Doses of Zinc and Hexavalent Chromium

V Latha - Mapana Journal of Sciences, 2024 - journals.christuniversity.in
Ecotoxicology is concerned with the possible long-term impacts of environmental stresses
that alter organisms at the genetic level. Earthworm coelomocytes are sensitive …