Health effects inflicted by chronic low‐level arsenic contamination in groundwater: A global public health challenge
Groundwater arsenic (As) contamination is a global public health concern. The high level of
As exposure (100‐1000 μg/L or even higher) through groundwater has been frequently …
As exposure (100‐1000 μg/L or even higher) through groundwater has been frequently …
Response of transposable elements to environmental stressors
IR Miousse, MCG Chalbot, A Lumen… - … Research/Reviews in …, 2015 - Elsevier
Transposable elements (TEs) comprise a group of repetitive sequences that bring positive,
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …
microRNA-21, via the HIF-1α/VEGF signaling pathway, is involved in arsenite-induced hepatic fibrosis through aberrant cross-talk of hepatocytes and hepatic stellate …
J Sun, L Shi, T Xiao, J Xue, J Li, P Wang, L Wu, X Dai… - Chemosphere, 2021 - Elsevier
Long-term exposure to arsenic, a widely distributed environmental toxicant, may result in
damage to various organs, including the liver. Mice exposed chronically to arsenite …
damage to various organs, including the liver. Mice exposed chronically to arsenite …
Transposable elements and stress in vertebrates: An overview
AM Pappalardo, V Ferrito, MA Biscotti… - International Journal of …, 2021 - mdpi.com
Since their identification as genomic regulatory elements, Transposable Elements (TEs)
were considered, at first, molecular parasites and later as an important source of genetic …
were considered, at first, molecular parasites and later as an important source of genetic …
Long INterspersed element‐1 mobility as a sensor of environmental stresses
B Del Re, G Giorgi - Environmental and Molecular Mutagenesis, 2020 - Wiley Online Library
Abstract Long INterspersed element (LINE‐1, L1) retrotransposons are the most abundant
transposable elements in the human genome, constituting approximately 17%. They move …
transposable elements in the human genome, constituting approximately 17%. They move …
Altering genomic integrity: heavy metal exposure promotes transposable element-mediated damage
ME Morales, G Servant, C Ade… - Biological trace element …, 2015 - Springer
Maintenance of genomic integrity is critical for cellular homeostasis and survival. The active
transposable elements (TEs) composed primarily of three mobile element lineages LINE-1 …
transposable elements (TEs) composed primarily of three mobile element lineages LINE-1 …
Reduced LINE-1 methylation is associated with arsenic-induced genotoxic stress in children
Early life exposure to arsenic has profound effect towards development of arsenic induced
toxic outcomes. Some districts in the state of West Bengal, India are highly affected by …
toxic outcomes. Some districts in the state of West Bengal, India are highly affected by …
Non-coding RNA therapeutics: Towards a new candidate for arsenic-induced liver disease
J Sun, L Wu, M Wu, Q Liu, H Cao - Chemico-Biological Interactions, 2023 - Elsevier
Arsenic, a metalloid toxicant, has caused serious environmental pollution and is presently a
global health issue. Long-term exposure to arsenic causes diverse organ and system …
global health issue. Long-term exposure to arsenic causes diverse organ and system …
Arsenic toxicity and epimutagenecity: the new LINEage
Global methylation pattern regulates the normal functioning of a cell. Research have shown
arsenic alter these methylation landscapes within the genome leading to aberrant gene …
arsenic alter these methylation landscapes within the genome leading to aberrant gene …
Transposable elements, placental development, and oocyte activation: Cellular stress and AMPK links jumping genes with the creation of human life
J Finley - Medical hypotheses, 2018 - Elsevier
Transposable elements (TEs), also known as “jumping genes”, are DNA sequences first
described by Nobel laureate Barbara McClintock that comprise nearly half of the human …
described by Nobel laureate Barbara McClintock that comprise nearly half of the human …