Diabetes has become more common in recent years worldwide, and this growth is projected
to continue in the future. The primary concern with diabetes is developing various …

Unhealthy dietary habits are major modifiable risk factors for the development of type 2
diabetes mellitus, a metabolic disease with increasing prevalence and serious …

Background: Obese ZSF-1 rats display many features of human type II diabetes including
nephropathy (DN). The study aimed to further understand the relevance of this model to DN …

Background Diabetic nephropathy and hepatopathy are health problems described by
specific renal and hepatic structure and function disturbances. The protective effects of the …

Type 2 diabetes mellitus (DM2) is a widespread metabolic disorder that results in podocyte
damage and diabetic nephropathy. Previous studies demonstrated that TRPC6 channels …

Background. Diabetic nephropathy (DN) is a common microvascular complication of
diabetes and a major cause of end‐stage renal disease, resulting in a substantial …

Diabetic nephropathy (DN) is a major microvascular complication of diabetes. Obesity and
hyperlipidemia, fueled by unhealthy food habits, are risk factors to glomerular filtration rate …

Although p53 is not essential for normal embryonic development, it plays a pivotal role in
many biological and pathological processes, including cell fate determination-dependent …

Objective Study the effect of the 3: 7 ratio of Astragalus total saponins and Curcumin on the
model of diabetic nephropathy rats, and explore its mechanisms. Methods Diabetic …

Animal models play a crucial role and are fundamentally required to advance the scientific
understanding and development of novel therapies for various human diseases and …