We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for
male fertility evaluation. While its detrimental implications on sperm function were …

It is becoming increasingly difficult to avoid exposure to man-made endocrine disrupting
chemicals (EDCs) and environmental toxicants. This escalating yet constant exposure is …

DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

Introduction Male infertility is a widespread disease with an etiology that is not always clear.
A number of studies have reported a decrease in sperm production in the last forty years …

Protamines are the major nuclear sperm proteins. The human sperm nucleus contains two
types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of …

For the appropriate protection of human health it is necessary to accurately estimate the
health effects of human exposure to toxic compounds. In the present review, epidemiological …

Objective To compare sperm DNA fragmentation (SDF) levels between testicular and
ejaculated sperm and to evaluate outcomes of intracytoplasmic sperm injection (ICSI) with …

Sperm deoxyribonucleic acid (DNA) damage has recently emerged as one of the most
controversial topics in male reproductive medicine. While level I evidence indicates that …