Excitotoxicity is one of the primary mechanisms of cell loss in a variety of diseases of the
central and peripheral nervous systems. Other than the previously established signaling …

Abstract N-methyl-D-aspartate (NMDA) receptors mediate a slow component of excitatory
synaptic transmission, are widely distributed throughout the central nervous system, and …

Alzheimer's disease (AD) is the most frequent cause of cognitive impairment in middle-aged
and older populations. There is a lack of drugs that demonstrate significant efficacy in AD, so …

Numerous molecular mechanisms are being examined in an attempt to discover disease-
modifying drugs to slow down the underlying neurodegeneration in Alzheimer's disease …

Glutamate, one of the most important excitatory neurotransmitters, acts as a signal
transducer in peripheral tissues and endocrine cells. Excessive glutamate secretion has …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive
decline and brain neuronal loss. A pioneering field of research in AD is brain stimulation via …

Platelets form complexes with gastric cancer (GC) cells via direct contact, enhancing their
malignant behavior. In the present study, the molecules responsible for GC cell-platelet …

This study aimed to determine if orally administered cannabidiol (CBD) lessens the cortical
over-release of glutamate induced by a severe traumatic brain injury (TBI) and facilitates …

Glutamate is a neurotransmitter that can cause excitatory neurotoxicity when its extracellular
concentration is too high, leading to disrupted calcium balance and increased production of …

Alzheimer's disease (AD) is one of the major neurodegenerative disorders, and its incidence
increases globally every year. Currently, available AD drugs symptomatically treat AD with …