The Role of Rosavin in the Pathophysiology of Bone Metabolism

P Wojdasiewicz, P Turczyn, A Lach-Gruba… - International Journal of …, 2024 - mdpi.com
Rosavin, a phenylpropanoid in Rhodiola rosea's rhizome, and an adaptogen, is known for
enhancing the body's response to environmental stress. It significantly affects cellular …

Rosavin: Research Advances in Extraction and Synthesis, Pharmacological Activities and Therapeutic Effects on Diseases of the Characteristic Active Ingredients of …

S Wang, Y Feng, L Zheng, P He, J Tan, J Cai, M Wu… - Molecules, 2023 - mdpi.com
Rhodiola rosea L.(RRL) is a popular plant in traditional medicine, and Rosavin, a
characteristic ingredient of RRL, is considered one of the most important active ingredients …

Therapeutic Promises of Bioactive Rosavin: A Comprehensive Review with Mechanistic Insight

A Aktar, S Bhuia, R Chowdhury, R Hasan… - Chemistry & …, 2024 - Wiley Online Library
Rosavin is an alkylbenzene diglycoside primarily found in Rhodiola rosea (L.),
demonstrating various pharmacological properties in a number of preclinical test systems …

High-level production of Rhodiola rosea characteristic component rosavin from D-glucose and L-arabinose in engineered Escherichia coli

L Li, M Liu, H Bi, T Liu - Metabolic Engineering, 2024 - Elsevier
Rosavin is the characteristic component of Rhodiola rosea L., an important medicinal plant
used widely in the world that has been reported to possess multiple biological activities …

Rosavin thwarts amyloid-β-induced macromolecular damages and neurotoxicity, exhibiting anti-Alzheimer's disease activity in Wister rat model

M Huang, R Sui, L Zhang, Y Zhu, X Yuan, H Jiang… - …, 2024 - Springer
Lately, interest surrounding the utilization of plant-derived compounds as a viable beneficial
approach for treating Alzheimer's disease (AD) has significantly increased. This study aimed …

Machine learning based identification potential feature genes for prediction of drug efficacy in nonalcoholic steatohepatitis animal model

M Matboli, I Abdelbaky, A Khaled, R Khaled… - Lipids in Health and …, 2024 - Springer
Abstract Background Nonalcoholic Steatohepatitis (NASH) results from complex liver
conditions involving metabolic, inflammatory, and fibrogenic processes. Despite its burden …

Comprehensive machine learning models for predicting therapeutic targets in type 2 diabetes utilizing molecular and biochemical features in rats

M Matboli, HS Al-Amodi, A Khaled, R Khaled… - Frontiers in …, 2024 - frontiersin.org
Introduction With the increasing prevalence of type 2 diabetes mellitus (T2DM), there is an
urgent need to discover effective therapeutic targets for this complex condition. Coding and …

Extracellular matrix turnover: phytochemicals target and modulate the dual role of matrix metalloproteinases (MMPs) in liver fibrosis

U Sabir, H Gu, DW Zhang - Phytotherapy Research, 2023 - Wiley Online Library
Extracellular matrix (ECM) resolution by matrix metalloproteinases (MMPs) is a well‐
documented mechanism. MMPs play a dual and complex role in modulating ECM …

Anti-Inflammatory Salidroside Delivery from Chitin Hydrogels for NIR-II Image-Guided Therapy of Atopic Dermatitis

S He, F Xie, W Su, H Luo, D Chen, J Cai… - Journal of Functional …, 2023 - mdpi.com
Atopic dermatitis (AD) is the most common heterogeneous skin disease. Currently, effective
primary prevention approaches that hamper the occurrence of mild to moderate AD have not …

Therapeutic effect of autophagy induced by rapamycin versus intermittent fasting in animal model of fatty liver

SA Hosny, MHA Moustafa… - Folia Histochemica et …, 2023 - journals.viamedica.pl
Abstract Introduction. High-fructose, high-fat diet consumption (HFHF) is one of the primary
causes of non-alcoholic fatty liver disease (NAFLD), which is due to impaired beta-oxidation …